Zofenoprilat is the active free sulfhydryl compound of Zenopril. Zenopril is an antioxidant that acts as an angiotensin-converting enzyme inhibitor. Endothelial membrane studies have demonstrated that Zofenoprilat induces the bradykinin B1 receptors, which activates the expression of FGF-2. Studies show that Zofenoprilat is more effective than Enalaprilat (sc-205669) at protecting pancreatic islets from extended high glucose exposure. We provide the Zofenoprilat Sodium Salt form.
1. Cushman, D.W., et al. 1989. Br J Clin Pharmacol. 28S: 115S-130S. PMID: 2557876
2. Borghi, C., et al. 2004. Expert Opin Pharmacother. 5: 1965-1977. PMID: 15330734
3. Lupi, R., et al. 2006. Eur. J. Endocrinol. 154: 355-361. PMID: 16452552
4. Donnini, S., et al. 2006. J. Pharmacol. Exp. Ther. 319: 515-522. PMID: 16868034
Santa Cruz Biotechnology, Inc. is a world leader in the development of products for the biomedical research market. Call us Toll Free at 1-800-457-3801.
Copyright © 2007-2019 Santa Cruz Biotechnology, Inc. All Rights Reserved. "Santa Cruz Biotechnology", and the Santa Cruz Biotechnology, Inc. logo, "Santa Cruz Animal Health", "San Juan Ranch", "Supplement of Champions", the San Juan Ranch logo, "Ultracruz", "Chemcruz", "Immunocruz", "Exactacruz", and "EZ Touch" are registered trademarks of Santa Cruz Biotechnology, Inc.
All trademarks are the property of their respective owners.