ZK 93423 hydrochloride CAS: 83910-44-5
MF: C23H22N2O4•HCl
MW: 426.9
A potent benzodiazepine agonist.

ZK 93423 hydrochloride (CAS 83910-44-5)

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Alternate Names: 4-(Methoxymethyl)-6-(phenylmethoxy)-9H-pyrido[3,4-b]indole-3-carboxylic acid ethyl ester hydrochloride
Application: ZK 93423 hydrochloride is a potent benzodiazepine agonist
CAS Number: 83910-44-5
Molecular Weight: 426.9
Molecular Formula: C23H22N2O4•HCl
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data (including water content).
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ZK 93423 hydrochloride is a potent benzodiazepine agonist. Non-selective with GABAA receptors containing α1-, α2-, α3- and α5-subunits.


References

Stephens et al (1984) Discriminative stimulus properties of b-carbolines characterized as agonists and inverse agonists at central benzodiazepine receptors. Psychopharmacology 83 233. File and Baldwin (1987) Effects of b-carbolines in animal models of anxiety. Brain Res.Bull. 19 293. Cox et al (1998) Synthesis and evaluation of analogues of the partial agonist 6-(propyloxy)-4-(methoxymethyl)-b-carboline-3-carboxylic acid ethyl ester (6-PBC) and the full agonist 6-(benzyloxy)-4-(methoxymethyl)-b-carboline-3-carboxylic acid ethyl ester (Zk 93423) at wild type and recombinant GABAA receptors. J.Med.Chem. 41 2537.

Physical State :
Solid
Solubility :
Soluble to 30 mM in DMSO and to 5 mM in Ethanol
Storage :
Desiccate at room temperature
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
SMILES :
CCOC(=O)C1=NC=C2C(=C1COC)C3=C(N2)C=CC(=C3)OCC4=CC=CC=C4.Cl

Download SDS (MSDS)

Certificate of Analysis

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