Anti-YAP1 Antibody (G-6) is a mouse monoclonal IgG1 κ YAP1 antibody, cited in 55 publications, provided at 200 µg/ml
raised against amino acids 206-330 mapping near the C-terminus of YAP of human origin
Anti-YAP1 Antibody (G-6) is recommended for detection of YAP of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA
Anti-YAP1 Antibody (G-6) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
TransCruz reagent for Gel Supershift and ChIP applications (sc-376830 X, 200 µg/0.1 ml)
Contact our Technical Service Department (or your local Distributor) for more information on how to receive a FREE 10 µg sample of YAP1 (G-6): sc-376830.
m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for YAP1 Antibody (G-6) for WB and IHC(P) applications. These reagents are now offered in bundles with YAP1 Antibody (G-6) (see ordering information below).
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possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
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Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
YAP Antibody (G-6) is a high quality monoclonal YAP antibody (also designated YAP1 antibody) suitable for the detection of the YAP protein of mouse, rat and human origin. YAP Antibody (G-6) is available as both the non-conjugated anti-YAP antibody form, as well as multiple conjugated forms of anti-YAP antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. The Yes-associated protein, otherwise known as YAP, is a 14-3-3-binding molecule that was originally recognized by virtue of its ability to bind to the SH3 domain of Yes. The binding of YAP to 14-3-3 requires the phosphorylation of a homologous serine residue (Ser 112) in the YAP 14-3-3-binding motif. The highly conserved and ubiquitously expressed 14-3-3 proteins regulate differentiation, cell cycle progression and apoptosis by binding intracellular phosphoproteins involved in signal transduction. YAP may link events at the plasma membrane and cytoskeleton to inhibition of transcription in the nucleus in a manner regulated by 14-3-3 proteins. YAP shares homology with the WW domain of TAZ, transcriptional co-activator with PDZ-binding motif, which functions as a transcriptional co-activator by binding to the PPXY motif present in transcription factors. YAP is expressed at high levels in the lung, placenta, prostate, ovary and testis.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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