Molecular structure of XE-CCG-I
XE-CCG-I
Alternate Names:
(1S,2S,3R)-2-[(S)-Amino(carboxy)methyl]-3-[2-(9H-xanthen-9-yl)ethyl]cyclopropanecarboxylic acid
Application:
XE-CCG-I is a selective and highly active group II mGluR antagonist with specificity towards the mGluR-3
Molecular Weight:
367.4
Molecular Formula:
C21H21NO5
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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Description
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SDS & Certificate of Analysis
XE-CCG-I selective and highly active group II mGluR antagonist with a subtype specificity towards the mGlu3 receptor. XE-CCG-I has no activity towards group I and group III mGluRs.
XE-CCG-I References
- Pharmacological agents acting at subtypes of metabotropic glutamate receptors. | Schoepp, DD., et al. 1999. Neuropharmacology. 38: 1431-76. PMID: 10530808
- Ligands for glutamate receptors: design and therapeutic prospects. | Bräuner-Osborne, H., et al. 2000. J Med Chem. 43: 2609-45. PMID: 10893301
- The metabotropic glutamate receptors: structure, activation mechanism and pharmacology. | Pin, JP. and Acher, F. 2002. Curr Drug Targets CNS Neurol Disord. 1: 297-317. PMID: 12769621
- (2S,1'S,2'R,3'R)-2-(2'-Carboxy-3'-hydroxymethylcyclopropyl) glycine is a highly potent group 2 and 3 metabotropic glutamate receptor agonist with oral activity. | Collado, I., et al. 2004. J Med Chem. 47: 456-66. PMID: 14711315
Inhibitor of:
mGluR-2, and mGluR-3.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
XE-CCG-I, 1 mg | sc-222421 | 1 mg | $110.00 |