XCT790 CAS: 725247-18-7
MF: C23H13F9N4O3S
MW: 596.42
A potent inverse agonist of ERRα.

XCT790 (CAS 725247-18-7)

XCT790 | CAS 725247-18-7 is rated 5.0 out of 5 by 1.
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Alternate Names: 3-[4-(2,4-bis-trifluoromethylbenzyloxy)-3-methoxyphenyl]-2-cyano-n-(5-trifluoromethyl-1,3,4-thiadiazol-2-yl)acrylamide
Application: XCT790 is a potent inverse agonist of ERRα
CAS Number: 725247-18-7
Purity: ≥98%
Molecular Weight: 596.42
Molecular Formula: C23H13F9N4O3S
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data (including water content).
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XCT790 is a potent and specific inverse agonist of ERRα. XCT790 shows no significant antagonist activity on related nuclear receptors, such as ERR or ERα at concentrations below 10 µM. This also inhibits the constitutive activity of ER (Estrogen Receptor).


References

Busch, B.B., et al., Identification of a selective inverse agonist for the orphan nuclear receptor estrogen-related receptor å. J. Med. Chem. 47, 5593-5596, (2004)

Physical State :
Solid
Solubility :
Solubility: Soluble in DMSO: 10 mg/mL
Storage :
Store at 4° C
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
MDL Number :
MFCD08277031
SMILES :
COC1=C(C=CC(=C1)/C=C(C#N)/C(=O)NC2=NN=C(S2)C(F)(F)F)OCC3=C(C=C(C=C3)C(F)(F)F)C(F)(F)F

Download SDS (MSDS)

Certificate of Analysis

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Rated 5 out of 5 by from Eskiocak B; et al Eskiocak B; et al. (PubMed ID: 24999922) determined that XCT790 potently activates AMP kinase. -SCBT Publication Review
Date published: 2015-05-27
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