Xanthurenic acidA potent activator of group II mGluRs

Xanthurenic acid (CAS 59-00-7)

Xanthurenic acid | CAS 59-00-7 is rated 5.0 out of 5 by 1.
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Application: A potent activator of group II mGluRs
CAS Number: 59-00-7
Purity: ≥95%
Molecular Weight: 205.17
Molecular Formula: C10H7NO4
* Refer to Certificate of Analysis for lot specific data (including water content).
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Xanthurenic acid selectively activates group II mGluRs in transfected HEK 293 cells at nanomolar concentrations. Xanthurenic acid is an activator of mGluR-2 and mGluR-3. Xanthurenic acid also attenuates cAMP formation in mouse cortical slices with mGluR-2 and mGluR-3 expression.

Appearance :
Powder
Physical State :
Solid
Storage :
Store at room temperature
Melting Point :
297-298° C (lit.)(dec.)
Boiling Point :
~514.4° C at 760 mmHg (Predicted)
Density :
~1.6 g/cm3 (Predicted)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
5699
SMILES :
C1=CC2=C(C(=C1)O)NC(=CC2=O)C(=O)O

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Certificate of Analysis

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Rated 5 out of 5 by from Perez Perez-Gonzalez et al. (PubMed ID 26224603) found that that the tryptophan metabolite, xanthurenic acid, was an efficient free radical scavenger. -SCBT Publication Review
Date published: 2015-04-05
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