WogoninAn anti-inflammatory agent and inhibitor of COX-2

Wogonin (CAS 632-85-9)

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Synonym: 5,7-Dihydroxy-8-methoxyflavone
Application: An anti-inflammatory agent and inhibitor of COX-2
CAS Number: 632-85-9
Molecular Weight: 284.26
Molecular Formula: C16H12O5
* Refer to Certificate of Analysis for lot specific data (including water content).
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An anti-inflammatory agent and inhibitor of COX-2, which blocks the induction of both COX-2 and iNOS. Wogonin inhibits COX-2 (IC50 = 46 µM) without affecting COX-1. Wogonin inhibits iNOS induction and thus inhibts activation-induced C6 glial cell death. S


References

Park, et al. Eur. J. Pharmacol. 425, 153-157, (2001); Chi, et al. Biochem. Pharmacol. 61, 1195-1203, (2001); Kim, et al. Neurosci. Lett. 309, 67-71, (2001)

Physical State :
Solid
Solubility :
Soluble in DMSO
Storage :
Store at 4° C
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
5281703
SMILES :
COC1=C(C=C(C2=C1OC(=CC2=O)C3=CC=CC=C3)O)O

Download SDS (MSDS)

Certificate of Analysis

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