WNK3 Antibody (4H5): sc-517063
- WNK3 Antibody (4H5) is a mouse monoclonal IgG2b κ WNK3 antibody provided at 100 µg/ml
- raised against amino acids 1-100 representing partial length WNK3 of human origin
- recommended for detection of WNK3 of human origin by WB, IP and ELISA
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for WNK3 Antibody (4H5). This work is in progress.
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WNK3 Antibody (4H5) is a mouse monoclonal IgG2b kappa light chain antibody that detects WNK3 protein of human origin by western blotting (WB), immunoprecipitation (IP), and enzyme-linked immunosorbent assay (ELISA). Anti-WNK3 antibody (4H5) is available as a non-conjugated format. WNK3 is a member of the WNK (with no lysine (K)) kinase family, which plays a crucial role in regulating ion transport and blood pressure homeostasis. WNK3 is involved in signaling pathways that modulate sodium and potassium channel activity, essential for maintaining cellular ion balance and overall cardiovascular health. Aberrant regulation of WNK3 has been linked to various pathophysiological conditions, including hypertension and renal disorders, highlighting its importance in both physiological and pathological processes. WNK3 is primarily expressed in the brain, where WNK3 contributes to neuronal signaling and function. Additionally, WNK kinases, including WNK3, share a highly conserved catalytic domain structure that is critical for enzymatic activity, allowing effective phosphorylation of target proteins. Understanding WNK3 function and regulation is vital for developing therapeutic strategies aimed at conditions associated with WNK3 dysregulation.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
WNK3 Antibody (4H5) | sc-517063 | 100 µg/ml | $322.00 |