Vitamin D2 is the synthetic form of Vitamin D and has been shown to aid in the absorption of calcium and phosphorus. Vitamin D2 has a strong inhibitory effect against bladder tumor promotion by sodium saccharin and induces cell differentiation in leukemia cells. Vitamin D2 has also been shown to be an inhibitor of DNA polymerase.
1. Yen, A., et al., 1991. 1,25-Dihydroxy vitamin D2 induces leukemia cell differentiation. In vitro cellular & developmental biology : journal of the Tissue Culture Association. 27A(7): 518-20. PMID: 1653778 2. Yazawa, Y., et al., 2000. Antitumor promoting effect of an active component of Polyporus, ergosterol and related compounds on rat urinary bladder carcinogenesis in a short-term test with concanavalin A. Biological & pharmaceutical bulletin. 23(11): 1298-302. PMID: 11085355
Soluble in ethanol (80 mg/ml at 25° C), water (<1 mg/ml at 25° C), methanol, DMF (~20 mg/ml), and DMSO (20 mg/ml at 25° C).
Store at 4° C
114-118° C (lit.)
1.03 g/cm3 at 20° C
α25/D 103°±3°, c = 1.5 in ethanol; α20/D 110°, c = 1.5 in ethanol; α20/D 105°±2°, c = 4 in ethanol; α20/D 101.5°, c = 1.25 in ethanol; α25/D 82.6°, c = 3 in acetone
Hepatitis C virus: EC5050 = 3.8 µM (Hepatitis C virus); Mammalian DNA polymerase A: IC50 = 123 mM
pKa: 18.38 (Predicted), pKb: -1.3 (Predicted)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
I would like to know that is it possible to produce Vitamin D2 (Ergocalciferol) in 50,000 IU (International Units). If yes, then what will be its cost for bulk production.
Asked by: Qazi Mustafa
Thank you for your question. We currently do provide Vitamin D2 (CAS 50-14-6): sc-205988 in a 1g and 5 g quantity, and the list price is on our website. Please note that this is a research-grade chemical, and it is not intended for Diagnostic or Therapeutic use.
Rated 5 out of
BennettBennett, L. et al. (PubMed 24204618) reported that Vitamin D2-enriched button mushroom (Agaricus bisporus) improves memory in both wild type and APPswe/PS1dE9 transgenic mice. -SCBT Publication Review
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