Vindesine sulfateA vinca alkaloid

Vindesine sulfate (CAS 59917-39-4)

Vindesine sulfate | CAS 59917-39-4 is rated 5.0 out of 5 by 1.
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Application: A vinca alkaloid
CAS Number: 59917-39-4
Molecular Weight: 852.02
Molecular Formula: C43H55N5O7 H2SO4
* Refer to Certificate of Analysis for lot specific data (including water content).
Submit a review for this product and receive 15 CruzCredits

Vindesine sulfate is a vinca alkaloid derived from vinblastine. Vindesine sulfate is an inhibitor of Tubulin.


References

Dancey J, Steward WP. Anticancer Drugs. 6:625-636 (1995). Kodani T, Ueoka H, Kiura K et al. Lung Cancer. 36:313-319 (2002).

Appearance :
Powder
Physical State :
Solid
Solubility :
Soluble in methanol, DMSO, water, and methyl alcohol.
Storage :
Store at -20° C
Melting Point :
>250° C
Refractive Index :
n20D 1.71 (Predicted)
IC50 :
LT12 tumor cell line: IC50 = 1 nM (rat); LNCaP: IC50 = 9.5 nM (human); P388: IC50 = 10 nM (mouse); L1210: IC50 = 20 nM (mouse)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
43116
Merck Index :
14: 9987
EC Number :
261-984-7
SMILES :
OS(O)(=O)=O.CC[C@]1(O)CC2CN(C1)CCC1=C(NC3=CC=CC=C13)[C@@](C2)(C(=O)OC)C1=C(OC)C=C2N(C)C3[C@]4(CCN5CC=C[C@](CC)([C@@H]45)[C@@H](O)[C@]3(O)C(N)=O)C2=C1

Download SDS (MSDS)

Certificate of Analysis

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Rated 5 out of 5 by from Pastore Pastore, S. et al. (PubMed 6223955) found that Vindesine sulfate increased the NK-mediated cytolytic effects of mouse lymphocytes against human K562 target cells in a 18-hr assay. -SCBT Publication Review
Date published: 2015-01-11
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