Valacyclovir HydrochlorideAn L-valine ester of acyclovir

Valacyclovir Hydrochloride (CAS 124832-27-5)

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Application: An L-valine ester of acyclovir
CAS Number: 124832-27-5
Purity: ≥98%
Molecular Weight: 360.80
Molecular Formula: C13H20N6O4 HCl
* Refer to Certificate of Analysis for lot specific data (including water content).
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Valacyclovir hydrochloride is an L-valine ester of acyclovir . Valacyclovir Hydrochloride is an inhibitor of DNA Polymerase.


References

Ormrod D, Scott LJ, Perry CM. Drugs. 59:839-63 (2000).

Appearance :
Crystalline powder
Physical State :
Solid
Solubility :
Soluble in DMSO (14 mg/ml at 25° C), water (170 mg/ml), ethanol (<1 mg/ml at 25° C), and methanol.
Storage :
Store at room temperature
Melting Point :
159-162° C
Refractive Index :
n20D 1.67 (Predicted)
IC50 :
PEPT1: IC50 = 0.4 mM (human)
Ki Data :
Oligopeptide transporter, kidney isoform: Ki= 0.17 mM (rat); PEPT1: Ki= 0.49 mM (human); Solute carrier family 15 member 1: Ki= 2.5 mM (rat)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
60772
Merck Index :
14: 9899
MDL Number :
MFCD01861507
SMILES :
CC(C)C(C(=O)OCCOCN1C=NC2=C1NC(=NC2=O)N)N.Cl

Download SDS (MSDS)

Certificate of Analysis

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