Usnic acid is an antimicrobial, antitumor enzyme inhibiting agent shown to uncouple oxidative phosphorylation in mouse-liver mitochondria. Usnic acid induces necrosis in certain cells.
1. Abo-Khatwa, A N., et al., 1996. Lichen acids as uncouplers of oxidative phosphorylation of mouse-liver mitochondria. Natural toxins. 4(2): 96-102. PMID: 8726330 2. Han, Derick., et al., 2004. Usnic acid-induced necrosis of cultured mouse hepatocytes: inhibition of mitochondrial function and oxidative stress. Biochemical pharmacology. 67(3): 439-51. PMID: 15037196
Soluble in water (<0.11 g/100ml), acetone (0.77 g/100ml), ethyl acetate (0.88 g/100ml), fural (7.32 g/100ml), and furfuryl alcohol (1.21 g/100ml).
Store at room temperature
~594.8° C at 760 mmHg (Predicted)
~1.50 g/cm3 (Predicted)
n20D 1.64 (Predicted)
α20/D +495.0°±10.0°, c = 0.7 in chloroform
pKa: 4 (Predicted)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
To place an order using RMB or to ship to mainland China, please visit www.scbio.cn