Urapidil HClCAS: 64887-14-5
MF: C20H29N5O3·HCl
MW: 423.9
An adrenergic α1-AR antagonist and a serotonin 5-HT1A (SR-1A) receptor agonist.

Urapidil HCl (CAS 64887-14-5)

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Application: An adrenergic α1-AR antagonist and a serotonin 5-HT1A (SR-1A) receptor agonist
CAS Number: 64887-14-5
Purity: 99%
Molecular Weight: 423.9
Molecular Formula: C20H29N5O3·HCl
* Refer to Certificate of Analysis for lot specific data (including water content).
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Urapiidil HCl is an AR (adrenergic α1-AR) antagonist and a SR-1A agonist. Urapidil has an alpha-blocking effect but, unlike other alpha-blockers, also has a central sympatholytic effect mediated via stimulation of SR-1A in the central nervous system.


References

1. van Zwieten, P.A. 1989. Am. J. Cardiol. 64: 117I-121I. PMID: 2554709
2. van Zwieten, P.A. 1996. Clin. Exp. Hypertens. 18: 291-303. PMID: 8743022
3. Li, S., et al. 2000. Zhonghua Wai Ke Za Zhi. 38: 287-290. PMID: 12828169

Physical State :
Solid
Solubility :
Soluble in water (50 mM).
Storage :
Store at room temperature
Melting Point :
249-250° C
Boiling Point :
549° C at 760 mmHg (Predicted)
pK Values :
pKb: 7.79 (Predicted)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
WGK Germany :
3
RTECS :
YQ9862000
PubChem CID :
167980
MDL Number :
MFCD00078601
SMILES :
CN1C(=CC(=O)N(C1=O)C)NCCCN2CCN(CC2)C3=CC=CC=C3OC.Cl

Download SDS (MSDS)

Certificate of Analysis

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