UK 14,304 tartrate CAS: 59803-99-5
MF: C11H10BrN5•C4H6O6
MW: 442.23
An α2-adrenoceptor agonist.

UK 14,304 tartrate (CAS 59803-99-5)

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Alternate Names: 5-Bromo-6-(2-imidazolin-2-ylamino)quinoxaline tartrate
Application: UK 14,304 tartrate is an α2-adrenoceptor agonist
CAS Number: 59803-99-5
Molecular Weight: 442.23
Molecular Formula: C11H10BrN5•C4H6O6
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data (including water content).

UK 14,304 tartrate is a water-soluble form UK 14,304. Full α2 adrenergic agonist.


References

Cambridge (1981) UK-14,304, a potent and selective alpha2-gonist for the characterisation of alpha-adrenoceptor subtypes. Eur.J.Pharmacol. 72 413. Andorn et al (1988) Specific [3H]UK-14,304 binding in human cortex occurs at multiple high affinity states with a2-adrenergic selectivity and different affinities for GTP. Life Sci. 43 1805. Macdonald et al (1997) Gene trageting - homing in on a2-adrenoceptor-subtype function. TiPS 18 211. Chopin et al (1999) Effects of alpha-2 adrenoceptor agonists and antagonists on circling behavior in rats with unilateral 6-hydroxydopamine lesions of the nigrostriatal pathway. J.Pharmacol.Exp.Ther. 288 798.

Physical State :
Solid
Solubility :
Soluble to 100 mM in Water
Storage :
Desiccate at room temperature
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
11236066
SMILES :
C1CN=C(N1)NC2=C(C3=NC=CN=C3C=C2)Br.C(C(C(=O)O)O)(C(=O)O)O

Download SDS (MSDS)

Certificate of Analysis

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