UK 14,304 tartrate is a water-soluble form UK 14,304. Full α2 adrenergic agonist.
Cambridge (1981) UK-14,304, a potent and selective alpha2-gonist for the characterisation of alpha-adrenoceptor subtypes. Eur.J.Pharmacol. 72 413. Andorn et al (1988) Specific [3H]UK-14,304 binding in human cortex occurs at multiple high affinity states with a2-adrenergic selectivity and different affinities for GTP. Life Sci. 43 1805. Macdonald et al (1997) Gene trageting - homing in on a2-adrenoceptor-subtype function. TiPS 18 211. Chopin et al (1999) Effects of alpha-2 adrenoceptor agonists and antagonists on circling behavior in rats with unilateral 6-hydroxydopamine lesions of the nigrostriatal pathway. J.Pharmacol.Exp.Ther. 288 798.
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