UA62784 CAS: 313367-92-9
MF: C23H15NO3
MW: 353.37
A centromere protein E (CENP-E) inhibitor.

UA62784 (CAS 313367-92-9)

  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getAggregateRating, 113ms
  • bvseo-msg: The resource to the URL or file is currently unavailable.;
Synonym: 4-[5-(4-Methoxyphenyl)-2-oxazolyl]-9H-Fluoren-9-one
Application: A centromere protein E (CENP-E) inhibitor
CAS Number: 313367-92-9
Purity: ≥98%
Molecular Weight: 353.37
Molecular Formula: C23H15NO3
* Refer to Certificate of Analysis for lot specific data (including water content).
Submit a review for this product and receive 15 CruzCredits

UA62784 is a fluorenone specific inhibitor of CENP-E(centromere protein E), which is a kinesin-like motor protein. It is known that CENP-E migrates towards the kinetochore during mitosis and is essential in spindle formation. UA62784 acts as a specific inhibitor of CENP-E via binding to the motor domain of the protein. As a result of this inhibition cell cycle arrest occurs during metaphase via inhibiting chromosome congregation at the metaphase plate. It is believed that this is a result of UA62784's ability to inhibit CENP-E microtubule associated ATPase activity. Furthermore, UA62784 can selectively destroy pancreatic cancer locus 4-deficient cancer cells.


1. Henderson, M.C., et al. 2009. Mol. Cancer Ther. 8: 36-44. PMID: 19139111
2. Wang, H., et al. 2009. Pancreas. 38: 551-557. PMID: 19276868

Appearance :
Physical State :
Solubility :
Solubility: Soluble in DMSO and Water
Storage :
Store at 4° C
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
MDL Number :

Download SDS (MSDS)

Certificate of Analysis

Adobe Acrobat Reader is required to reliably view,
print and comment on PDF documents

  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getContent, 115ms
  • bvseo-msg: The resource to the URL or file is currently unavailable.;
  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getReviews, 19ms
  • bvseo-msg: The resource to the URL or file is currently unavailable.;

Santa Cruz Biotechnology, Inc. is a world leader in the development of products for the biomedical research market. Call us Toll Free at 1-800-457-3801.
Copyright © 2007-2020 Santa Cruz Biotechnology, Inc. All Rights Reserved. "Santa Cruz Biotechnology", and the Santa Cruz Biotechnology, Inc. logo, "Santa Cruz Animal Health", "San Juan Ranch", "Supplement of Champions", the San Juan Ranch logo, "Ultracruz", "Chemcruz", "Immunocruz", "Exactacruz", and "EZ Touch" are registered trademarks of Santa Cruz Biotechnology, Inc.
All trademarks are the property of their respective owners.