U 90042 CAS: 134516-99-7
MF: C17H13ClN6O
MW: 352.78
A GABAA receptor ligand.

U 90042 (CAS 134516-99-7)

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Application: U 90042 is a GABAA receptor ligand
CAS Number: 134516-99-7
Molecular Weight: 352.78
Molecular Formula: C17H13ClN6O
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data (including water content).
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U 90042 is a GABAA receptor ligand that binds with comparable affinities to three receptor subtypes: α1β2γ2, α3β2γ2 and α6β2γ2 (Ki values are 7.8, 9.5 and 11.0 nM respectively). U 90042 potentiates GABA-induced chloride currents in α6β2γ2 receptors. Sedative/hypnotic compound


References

Tang et al (1995) U-90042, a sedative/hypnotic compound that interacts differentially with the GABAA receptor subtypes. J.Pharmacol.Exp.Ther. 275 761.

Solubility :
Soluble to 30 mM in DMSO and to 5 mM in Ethanol
Storage :
Store at room temperature
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
SMILES :
C1CC1C2=NC(=NO2)C3=C4N5CCN=C5C6=C(N4C=N3)C=CC(=C6)Cl

Download SDS (MSDS)

Certificate of Analysis

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