(+)-Tubocurarine dichlorideA neuromuscular block inducer

(+)-Tubocurarine dichloride (CAS 57-94-3)

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Application: A neuromuscular block inducer
CAS Number: 57-94-3
Purity: ≥99%
Molecular Weight: 681.7
Molecular Formula: C37H41ClN2O6•HCl
Supplemental Information: This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
* Refer to Certificate of Analysis for lot specific data (including water content).
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(+)-Tubocurarine dichloride induces neuromuscular block through interaction with acetylcholine receptor. (+)-Tubocurarine dichloride is an inhibitor of AChR, GABA Receptor,SR and HTR3.


References

Curare Alkaloids from Chondodendron tomentosum Ruiz and Pavon: J. D. Dutcher; JACS 68, 419 (1946) Neuromuscular block: W.C. Bowman; Br J Pharmacol 147 Suppl 1, S277 (2006) : W.C. Bowman; Br. J. Pharmacol. 147, S277 (2006

Physical State :
Solid
Solubility :
Soluble in water (50 mg/ml), alcohol (1:30), 100% ethanol, and DMSO (10 mM).
Storage :
Desiccate at 4° C
Melting Point :
275-280° C
Optical Activity :
α23/D +190°, c = 0.785 in methanol; α20/D +192.5°±2.5°, c = 1 in water
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
RTECS :
YO4900000
Merck Index :
14: 9807
MDL Number :
MFCD00013471
EC Number :
200-356-9
SMILES :
Cl.[Cl-].COC1=CC2=C3[C@@H](CC4=CC=C(O)C(OC5=C(OC)C=C6CCN(C)[C@@H](CC7=CC=C(OC3=C1O)C=C7)C6=C5)=C4)[N+](C)(C)CC2

Download SDS (MSDS)

Certificate of Analysis

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