Trypsin Inhibitor, soybean CAS: 9035-81-8

Trypsin Inhibitor, soybean (CAS 9035-81-8)

Trypsin Inhibitor, soybean | CAS 9035-81-8 is rated 5.0 out of 5 by 1.
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Alternate Names: Trypsin Inhibitor, soybean is also known as SBTI.
Application: Trypsin Inhibitor, soybean is a protein and inhibitor of trypsin factor Xa, plasmin and neutrophil elastase.
CAS Number: 9035-81-8
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data (including water content).
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Trypsin Inhibitor, soybean (STI) is a protein which reduces trypsin (a proteolytic enzyme) as well as plasma kallikrein and plasmin. activity. Trypsin Inhibitor, soybean has demonstrated inhibition of human neutrophil elastase at an IC50=0.3nM. At this concentration Trypsin Inhibitor, soybean showed neither cytotoxic nor haemolytic effects on populations of human blood cells. In fibrin matrix, and without toxic effects, Trypsin Inhibitor, soybean had strong inhibitory effect on human umbilical vein endothelial cells migration and tubulogenesis. It has been observed that repeated administration of Trypsin Inhibitor, soybean to rats, especially suckling and young rats, causes the pancreas to enlarge. Trypsin Inhibitor, soybean is also known as SBTI, STI, and Trypsin inhibitor from Glycine max.


References

1. Wilson, P.A., et al. 1978. Gut. 19: 260-266. PMID: 348580

2. Shakiba, Y., et al. 2007. Fitoterapia. 78: 587-589. PMID: 17590534

3. Ribeiro, J.K., et al. 2010. Eur J Pharmacol. PMID: 20624384

Appearance :
Powder
Physical State :
Solid
Derived From :
Soy Bean
Solubility :
Soluble in water (10 mg/ml), phosphate buffers (10 mg/ml), and balanced salt solutions (1 mg/ml).
Storage :
Store at 4° C
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
WGK Germany :
3
MDL Number :
MFCD00082103
EC Number :
232-906-9

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Certificate of Analysis

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Trypsin Inhibitor, soybean (CAS 9035-81-8)  Product Citations

See how others have used Trypsin Inhibitor, soybean (CAS 9035-81-8). Click on the entry to view the PubMed entry .

Citations 1 to 10 of 14 total

PMID: # 34948204  Prüschenk, S.|Majer, M.|Schreiber, R.|Schlossmann, J.| et al. 2021. Int J Mol Sci. 22:

PMID: # 33407092  Bautista-Amorocho, H.|Silva-Sayago, JA.|Goyeneche-Patino, DA.|Pérez-Cala, TL.|Macías-Gómez, F.|Arango-Viana, JC.|Martínez, A.| et al. 2021. BMC Mol Cell Biol. 22: 1.

PMID: # 18466892  Psenicka, M. et al. 2008. Cryobiology. 56: 251-253.

PMID: # 17640870  Conners, R. et al. 2007. J. Biol. Chem. 282: 27760-27768.

PMID: # 17171473  Oshima, K. et al. 2007. J. Assoc. Res. Otolaryngol. 8: 18-31.

PMID: # 16319066  Harikumar, KG. et al. 2006. J. Biol. Chem. 281: 2543-2550.

PMID: # 16982799  Csordás, G. et al. 2006. J. Cell Biol. 174: 915-921.

PMID: # 15644453  Taylor, EB. et al. 2005. Am. J. Physiol. Endocrinol. Metab. 288: E1055-E1061.

PMID: # 16228192  Wang, KJ. et al. 2005. Theor. Appl. Genet. 112: 66-71.

PMID: # 15382080  Kobayashi, H. et al. 2004. Int. J. Cancer. 112: 519-524.

Citations 1 to 10 of 14 total
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Rated 5 out of 5 by from Kobayashi Kobayashi, et. al. (PubMed ID 15168733) used soy bean trypsin inhibitor to study its effect on enzymatic activity of secreted, extracellular uPA. -SCBT Publication Review
Date published: 2015-03-20
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