Anti-TRPC3 Antibody (C-5) is a mouse monoclonal IgG2a κ TRPC3 antibody, cited in 5 publications, provided at 200 µg/ml
raised against amino acids 1-100 mapping at the N-terminus of TRPC3 of human origin
Anti-TRPC3 Antibody (C-5) is recommended for detection of TRPC3 of mouse, rat and human origin by WB, IP, IF and ELISA
Anti-TRPC3 Antibody (C-5) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
Contact our Technical Service Department (or your local Distributor) for more information on how to receive a FREE 10 µg sample of TRPC3 (C-5): sc-514670.
m-IgG Fc BP-HRP and m-IgG2a BP-HRP are the preferred secondary detection reagents for TRPC3 Antibody (C-5) for WB applications. These reagents are now offered in bundles with TRPC3 Antibody (C-5) (see ordering information below).
Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
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Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
TRPC3 Antibody (C-5) is a high quality monoclonal TRPC3 antibody (also designated TRP3 antibody) suitable for the detection of the TRPC3 protein of mouse, rat and human origin. TRPC3 Antibody (C-5) is available as both the non-conjugated anti-TRPC3 antibody form, as well as multiple conjugated forms of anti-TRPC3 antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. Transient receptor potential cation (TRPC) channels are a superfamily of six transmembrane segment-spanning, gated cation channels. TRPC subtypes mediate store-operated Ca2+ entry, a process involving Ca2+ influx and replenishment of Ca2+ stores formerly emptied through the action of inositol 1,4,5-trisphosphate production and other Ca2+ mobilizing agents. TRPC ion channels influence calcium-depletion induced calcium influx processes in response to chemo-, mechano- and osmoregulatory events. Human TRPC3 protein, also known as TRP3, is a cation channel that is predominantly expressed in brain. The activation of store-mediated Ca2+ entry in human cells likely occurs through the association between IP3R (inositol 1,4,5-trisphosphate receptors) and TRPC3. TRPC3 activity is also activated by DAG (diacylglycerol) independently of PKC (protein kinase C). Human TRPC6 is predominantly expressed in placenta, spleen, lung, small intestine and ovary. Also activated by diacylglycerol (DAG), TRPC6 comprises the a1-adrenoceptor-activated Ca(2+)-permeable cation channel.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences