raised against amino acids 51-160 of Troponin C of human origin
Anti-Troponin C fast skeletal Antibody (E-7) is recommended for detection of fast skeletal isoform of Troponin C of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA
Anti-Troponin C fast skeletal Antibody (E-7) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
See m-IgGκ BP-HRP (mouse IgGκ binding protein-HRP), our highly recommended recombinant alternative to conventional secondary anti-mouse IgG reagents.
Contact our Technical Service Department (or your local Distributor) for more information on how to receive a FREE 10 µg sample of Troponin C fast skeletal (E-7): sc-48347.
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Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
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Labware ships FedEx Ground free of charge to the contiguous US
Troponin C fast skeletal Antibody (E-7) is a high quality monoclonal Troponin C fast skeletal antibody (also designated Troponin C fast skeletal antibody) suitable for the detection of the Troponin C fast skeletal protein of mouse, rat and human origin. Troponin C fast skeletal Antibody (E-7) is available as both the non-conjugated anti-Troponin C fast skeletal antibody form, as well as multiple conjugated forms of anti-Troponin C fast skeletal antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. Actin is a highly conserved protein that is expressed in all eukaryotic cells. Actin filaments can form both stable and labile structures and are crucial components of microvilli and the contractile apparatus of muscle cells. Myosin is a hexamer of 2 heavy chains (MHC) and 4 light chains (MLC) that interacts with actin to generate the force for diverse cellular movements, including cytokinesis, phagocytosis and muscle contraction. Troponin facilitates the interaction between actin and myosin by binding to calcium. Troponin is made up of at least two subunits, which are divergent in cardiac muscle, fast skeletal muscle and slow skeletal muscle. Structures of skeletal muscle troponin are composed of Troponin C (the sensor), Troponin I (the regulator), and Troponin T (the link to the muscle thin filament). Troponin C is dumbbell-shaped and has a hydrophobic pocket that increases the contractile force of muscle fibers. Troponin C has 2 isoforms: fast and slow. Troponin C fast skeletal has two calcium binding sites while slow/cardiac Troponin C has a single calcium binding site.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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