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Tris(trimethylsilyl)amine is a strong, non-nucleophilic base that is used as a reagent in organic synthesis. It functions as a Lewis base, readily donating its lone pair of electrons to various electrophiles. In this capacity, it is employed in the deprotonation of acidic compounds, such as alcohols, phenols, and carboxylic acids, to form the corresponding alkoxides or phenoxides. It can be utilized in the synthesis of organosilicon compounds, where it acts as a nucleophile in the formation of carbon-silicon bonds. Tris(trimethylsilyl)amine′s mode of action involves its interaction with acidic protons, leading to the formation of stable, negatively charged intermediates. This reactivity makes it useful in the preparation of a wide range of organosilicon and organic compounds, contributing to the advancement of methodologies in chemical and development.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Tris(trimethylsilyl)amine, 5 g | sc-229652 | 5 g | $51.00 |