Tris DBA chloroform adduct is an n-myristoyltransferase-1 (NMT1) inhibitor that prevents activation of MAPK, PI 3-K and STAT3 signaling pathways. It can be used as a cyclization catalyst. Tris DBA chloroform adduct also exhibits antiproliferative activity against melanoma cells in vitro.
1. Bhandarkar, Sulochana S., et al., 2008. Tris (dibenzylideneacetone) dipalladium, a N-myristoyltransferase-1 inhibitor, is effective against melanoma growth in vitro and in vivo. Clinical cancer research : an official journal of the American Association for Cancer Research. 14(18): 5743-8. PMID: 18794083
Santa Cruz Biotechnology, Inc. is a world leader in the development of products for the biomedical research market. Call us Toll Free at 1-800-457-3801.
Copyright © 2007-2019 Santa Cruz Biotechnology, Inc. All Rights Reserved. "Santa Cruz Biotechnology", and the Santa Cruz Biotechnology, Inc. logo, "Santa Cruz Animal Health", "San Juan Ranch", "Supplement of Champions", the San Juan Ranch logo, "Ultracruz", "Chemcruz", "Immunocruz", "Exactacruz", and "EZ Touch" are registered trademarks of Santa Cruz Biotechnology, Inc.
All trademarks are the property of their respective owners.