Tris DBA chloroform adduct

Tris DBA chloroform adduct (CAS 52522-40-4)

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Synonym: Tris(dibenzylideneacetone)dipalladium(0)-chloroform adduct; Pd2(dba)3⋅CHCl3
Application: An NMT1 inhibitor with antiproliferative properties
CAS Number: 52522-40-4
Molecular Weight: 1035.10
Molecular Formula: Pd2(C17H14O)3•CHCl3
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Tris DBA chloroform adduct is an n-myristoyltransferase-1 (NMT1) inhibitor that prevents activation of MAPK, PI 3-K and STAT3 signaling pathways. It can be used as a cyclization catalyst. Tris DBA chloroform adduct also exhibits antiproliferative activity against melanoma cells in vitro.


1. Bhandarkar, Sulochana S., et al., 2008. Tris (dibenzylideneacetone) dipalladium, a N-myristoyltransferase-1 inhibitor, is effective against melanoma growth in vitro and in vivo. Clinical cancer research : an official journal of the American Association for Cancer Research. 14(18): 5743-8. PMID: 18794083

Physical State :
Solubility :
Insoluble in water.
Storage :
Store at room temperature
Melting Point :
131-135° C (lit.)
Boiling Point :
400.7° C at 760 mmHg
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
WGK Germany :
PubChem CID :
MDL Number :

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