Date published: 2026-5-15

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Trimesic acid (CAS 554-95-0)

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Alternate Names:
Benzene-1,3,5-tricarboxylic acid; BTC
Application:
Trimesic acid is a planar benzoic acid with antiviral and chemical transport properties
CAS Number:
554-95-0
Purity:
≥98%
Molecular Weight:
210.14
Molecular Formula:
C9H6O6
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Trimesic acid is an organic compound characterized by a benzene ring with three carboxyl groups (COOH) attached. Its presence holds significant importance as a structural element in various natural and synthetic materials, encompassing polymers, resins, and dyes. Moreover, this compound plays a role in the synthesis of diverse molecules, including pharmaceuticals, dyes, and fragrances. Trimesic acidexhibits notable inhibitory effects on several enzymes, such as cytochrome P450 and cytochrome c oxidase. By binding to the active sites of these enzymes, it effectively hinders their catalytic activity, impeding the progression of their respective reactions. Furthermore, Trimesic acid has been observed to bind to and inhibit the function of various proteins, including transcription factors and receptors. These interactions further contribute to the compound′s broad range of effects in biological systems.


Trimesic acid (CAS 554-95-0) References

  1. Trimesic acid coated alumina: an efficient multi-cyclic adsorbent for toxic Cu(II).  |  Saha, B., et al. 2008. J Colloid Interface Sci. 320: 30-9. PMID: 18255092
  2. Adsorption and surface complexation of trimesic acid at the alpha-alumina-electrolyte interface.  |  Borah, JM. and Mahiuddin, S. 2008. J Colloid Interface Sci. 322: 6-12. PMID: 18407283
  3. catena-Poly[[tetraaquanickel(II)]-μ(3)-benzene-1,3,5-tricarboxylato-3':1:2-κO:O,O:O-[tetraaquanickel(II)]-μ(2)-benzene-1,3,5-tricarboxylato-2:3κO:O-[tetraaquanickel(II)]].  |  Hsu, SC., et al. 2009. Acta Crystallogr Sect E Struct Rep Online. 65: m625-6. PMID: 21582995
  4. Quantification of trimesic acid in liver, spleen and urine by high-performance liquid chromatography coupled to a photodiode-array detection.  |  Baati, T., et al. 2011. J Chromatogr B Analyt Technol Biomed Life Sci. 879: 2311-4. PMID: 21727049
  5. Bias-induced conformational switching of supramolecular networks of trimesic acid at the solid-liquid interface.  |  Ubink, J., et al. 2018. J Chem Phys. 148: 174703. PMID: 29739202
  6. Efficient removal of uranium using a melamine/trimesic acid-modified hydrothermal carbon-based supramolecular organic framework.  |  Li, H., et al. 2019. J Colloid Interface Sci. 544: 14-24. PMID: 30822602
  7. Synthesis and optimization of the trimesic acid modified polymeric carbon nitride for enhanced photocatalytic reduction of CO2.  |  Hayat, A., et al. 2019. J Colloid Interface Sci. 548: 197-205. PMID: 31003166
  8. Cathodic electrodeposited Cu-BTC MOFs assembled from Cu(II) and trimesic acid for electrochemical determination of bisphenol A.  |  Hu, P., et al. 2020. Mikrochim Acta. 187: 145. PMID: 31970521
  9. Morphological Evolution of Two-Dimensional Porous Hexagonal Trimesic Acid Framework.  |  Tothadi, S., et al. 2020. ACS Appl Mater Interfaces. 12: 15588-15594. PMID: 32155330
  10. New curcumin-trimesic acid cocrystal and anti-invasion activity of curcumin multicomponent solids against 3D tumor models.  |  Sathisaran, I., et al. 2020. Int J Pharm. 587: 119667. PMID: 32702448
  11. Sodium Chloroacetate Modified Polyethyleneimine/Trimesic Acid Nanofiltration Membrane to Improve Antifouling Performance.  |  Gu, K., et al. 2021. Membranes (Basel). 11: PMID: 34564521
  12. Carbonyl hypoiodites from pivalic and trimesic acid and their silver(I) intermediates.  |  Ward, JS., et al. 2022. Dalton Trans. 51: 14646-14653. PMID: 36093683
  13. Thermodynamics of self-assembled molecular layers of trimesic acid from fields-supported kinetic Monte Carlo simulation.  |  Ustinov, EA., et al. 2022. Phys Chem Chem Phys. 24: 26111-26123. PMID: 36274631
  14. Correction: Mixing behavior of p-terphenyl-3,5,3',5'-tetracarboxylic acid with trimesic acid at the solid-liquid interface.  |  Li, W., et al. 2023. Phys Chem Chem Phys. 25: 5291. PMID: 36723146
  15. Chitosan Hydrogels Cross-Linked with Trimesic Acid for the Delivery of 5-Fluorouracil in Cancer Therapy.  |  Emani, S., et al. 2023. Pharmaceutics. 15: PMID: 37111570

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Trimesic acid, 100 g

sc-251341
100 g
$104.00