Date published: 2026-5-31

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Trihydroxycoprostane (CAS 547-96-6)

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Alternate Names:
(3α,5β,7α,12α)-Cholestane-3,7,12-triol; 3α,7α,12α-Trihydroxycoprostane
Application:
Trihydroxycoprostane is a substrate for the sterol 27-hydroxylase enzyme
CAS Number:
547-96-6
Molecular Weight:
420.67
Molecular Formula:
C27H48O3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Trihydroxycoprostane is a bile acid metabolite used in biochemical research for the study of lipid digestion and absorption processes. Researchers apply this compound to explore the role of bile acids in the emulsification and breakdown of dietary fats, which is a fundamental aspect of gastrointestinal physiology. In the field of analytical chemistry, Trihydroxycoprostane is often used as a standard to identify and quantify bile acids in biological samples via chromatographic techniques. The compound is also of interest in metabolic studies that investigate the enterohepatic circulation of bile acids and their regulation. Moreover, in liver function research, Trihydroxycoprostane is pertinent in understanding the synthesis and flow of bile acids and their impact on hepatic health.


Trihydroxycoprostane (CAS 547-96-6) References

  1. STERO-BILE ACIDS AND BILE STEROLS. LXI. METABOLISM OF LITHOCHOLIC ACID IN HOG LIVER PREPARATION.  |  KURATA, Y. 1964. J Biochem. 55: 415-9. PMID: 14170094
  2. Membrane continuities involving chloroplasts and other organelles in plant cells.  |  Crotty, WJ. and Ledbetter, MC. 1973. Science. 182: 839-41. PMID: 17772160
  3. High fat diet incorporated with meat proteins changes biomarkers of lipid metabolism, antioxidant activities, and the serum metabolomic profile in Glrx1-/- mice.  |  Ahmad, MI., et al. 2020. Food Funct. 11: 236-252. PMID: 31956867
  4. Bile salts and liver disease in childhood.  |  Javitt, NB. 1974. Postgrad Med J. 50: 354-61. PMID: 4464509
  5. Porphyrin-heme pathway: regulation by intermediates in bile acid synthesis.  |  Javitt, NB., et al. 1973. Science. 182: 841-2. PMID: 4795750

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Trihydroxycoprostane, 1 mg

sc-213115
1 mg
$350.00