Date published: 2025-10-8

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Triadimefon (CAS 43121-43-3)

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Alternate Names:
Bayleton; Azocene; Fenxiunin; Haleton; Acizol; Adifon; Amiral
Application:
Triadimefon is an antifungal cytochrome P450 inhibitor
CAS Number:
43121-43-3
Purity:
≥96%
Molecular Weight:
293.75
Molecular Formula:
C14H16ClN3O2
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Triadimefon is a widely used fungicide. Triadimefon is also a cytochrome P450 (CYP) inhibitor, and induces brassinosteroid deficiency in plants. Its mode of action involves the inhibition of lanosterol 14α-demethylase, which disrupts oxidative demethylation reactions within the ergosterol biosynthesis pathway of fungi. Additionally, it hinders gibberellin biosynthesis.


Triadimefon (CAS 43121-43-3) References

  1. Triadimefon, a fungicidal triazole-type P450 inhibitor, induces brassinosteroid deficiency-like phenotypes in plants and binds to DWF4 protein in the brassinosteroid biosynthesis pathway.  |  Asami, T., et al. 2003. Biochem J. 369: 71-6. PMID: 12350224
  2. Triadimefon supports conditioned cue preference.  |  Holden, JM., et al. 2011. Behav Brain Res. 221: 307-10. PMID: 21396967
  3. Stereoselective bioaccumulation, transformation, and toxicity of triadimefon in Scenedesmus obliquus.  |  Xu, P. and Huang, L. 2017. Chirality. 29: 61-69. PMID: 28009445
  4. Enantioselective metabolism of triadimefon and its chiral metabolite triadimenol in lizards.  |  Shen, Q., et al. 2017. Ecotoxicol Environ Saf. 143: 159-165. PMID: 28535441
  5. Effect of triadimefon and its metabolite on adult amphibians Xenopus laevis.  |  Zhang, W., et al. 2020. Chemosphere. 243: 125288. PMID: 31743868
  6. Comparing the effect of triadimefon and its metabolite on male and female Xenopus laevis: Obstructed growth and gonad morphology.  |  Zhang, W., et al. 2020. Chemosphere. 259: 127415. PMID: 32603964
  7. Triadimefon triggers circling behavior and conditioned place preference/aversion in zebrafish in a dose dependent manner.  |  Paredes-Zúñiga, S., et al. 2021. Neurotoxicol Teratol. 86: 106979. PMID: 33839247
  8. Uptake and translocation of triadimefon by wheat (Triticum aestivum L.) grown in hydroponics and soil conditions.  |  Sumei, Y., et al. 2022. J Hazard Mater. 423: 127011. PMID: 34461532
  9. Triadimefon suppresses fetal adrenal gland development after in utero exposure.  |  Xu, Q., et al. 2021. Toxicology. 462: 152932. PMID: 34508824
  10. Triadimefon increases fetal Leydig cell proliferation but inhibits its differentiation of male fetuses after gestational exposure.  |  Lin, L., et al. 2021. Ecotoxicol Environ Saf. 228: 112942. PMID: 34737156
  11. Effect of triadimefon on rat placental morphology, function, and gene expression.  |  Chen, Q., et al. 2022. Toxicol Lett. 371: 25-37. PMID: 36179991
  12. Beneficial effects of triadimefon in overcoming drought stress in soybean at fluorescence stage.  |  Xu, B., et al. 2023. J Plant Physiol. 287: 154015. PMID: 37301038
  13. Triadimefon and triadimenol: effects on monoamine uptake and release.  |  Walker, QD. and Mailman, RB. 1996. Toxicol Appl Pharmacol. 139: 227-33. PMID: 8806838

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Triadimefon, 5 g

sc-204923
5 g
$94.00

Triadimefon, 10 g

sc-204923A
10 g
$150.00