Tracazolate hydrochloride CAS: 1135210-68-2
MF: C16H24N4O2•HCl
MW: 340.85
A modulator of GABAA receptors.

Tracazolate hydrochloride (CAS 1135210-68-2)

  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getAggregateRating, 106ms
  • REVIEWS, PRODUCT
  • bvseo-msg: The resource to the URL or file is currently unavailable.;
Alternate Names: ICI 136753
Application: Tracazolate hydrochloride is a modulator of GABAA receptors
CAS Number: 1135210-68-2
Purity: ≥99%
Molecular Weight: 340.85
Molecular Formula: C16H24N4O2•HCl
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data (including water content).
loading

Tracazolate hydrochloride is a subtype selective GABAA allosteric receptor modulator. Can potentiate or inhibit recombinant GABAA function depending on subunit combination. Tracazolate hydrochloride enhances native GABAA receptor function.


References

1. Meiners, B.A. and Salama, A.I. 1982. Eur. J. Pharmacol. 78: 315-322.
2. Patel, J.B. and Malick, J.B. 1982. Eur. J. Pharmacol. 78: 323-333.
3. Thompson, S.A., et al. 2002. Mol. Pharmacol. 61: 861-869.

Physical State :
Solid
Solubility :
Soluble in 1eq. HCl (100 mM).
Storage :
Desiccate at room temperature
Refractive Index :
n20D 1.58 (Predicted)
IC50 :
Plasmodium falciparum: IC50 = 10 µM
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
EC Number :
255-214-9
SMILES :
CCCCNC1=C2C=NN(C2=NC(=C1C(=O)OCC)C)CC.Cl

Download SDS (MSDS)

Certificate of Analysis

Adobe Acrobat Reader is required to reliably view,
print and comment on PDF documents

Tracazolate hydrochloride (CAS 1135210-68-2)  Product Citations

See how others have used Tracazolate hydrochloride (CAS 1135210-68-2). Click on the entry to view the PubMed entry .

Citations 1 to 1 of 1 total

PMID: # 31180326  Elife.

Citations 1 to 1 of 1 total
  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getContent, 97ms
  • QUESTIONS, PRODUCT
  • bvseo-msg: The resource to the URL or file is currently unavailable.;
  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getReviews, 6ms
  • REVIEWS, PRODUCT
  • bvseo-msg: The resource to the URL or file is currently unavailable.;