Tracazolate hydrochloride is a subtype selective GABAA allosteric receptor modulator. Can potentiate or inhibit recombinant GABAA function depending on subunit combination. Tracazolate hydrochloride enhances native GABAA receptor function.
1. Meiners, B.A. and Salama, A.I. 1982. Eur. J. Pharmacol. 78: 315-322. 2. Patel, J.B. and Malick, J.B. 1982. Eur. J. Pharmacol. 78: 323-333. 3. Thompson, S.A., et al. 2002. Mol. Pharmacol. 61: 861-869.
Soluble in 1eq. HCl (100 mM).
Desiccate at room temperature
n20D 1.58 (Predicted)
Plasmodium falciparum: IC50 = 10 µM
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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