TPBM CAS: 6466-43-9
MF: C15H16N4O2S
TPBM is a potent inhibitor of estrogen receptor α.

TPBM (CAS 6466-43-9)

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Alternate Names: Theophylline, 8-[(benzylthio)methyl]
Application: TPBM is a potent inhibitor of estrogen receptor α
CAS Number: 6466-43-9
Purity: ≥97%
Molecular Weight: 316.38
Molecular Formula: C15H16N4O2S
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data (including water content).
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TPBM is an effective inhibitor of the alpha estrogen receptor via blockage of the ER-alpha dinging to consensus estrogen response element DNA. Displays minimal cellular toxicity and no effect on estrogen-independent cell growth.


References

1. Mao, C. et al. 2008. J. Biol. Chem. 283(19): 12819-12830. PMID: 18337247

Physical State :
Solid
Solubility :
Soluble in DMSO: >5 mg/mL
Storage :
Store at room temperature
Boiling Point :
~509.6° C at 760 mmHg (Predicted)
Density :
~1.4 g/cm3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
SMILES :
CN1C2=C(C(=O)N(C1=O)C)NC(=N2)CSCC3=CC=CC=C3

Download SDS (MSDS)

Certificate of Analysis

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