Tocopherylquinone, d-alphaA vitamin E oxidation product with antioxidant activities

Tocopherylquinone, d-alpha (CAS 7559-04-8)

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Application: A vitamin E oxidation product with antioxidant activities
CAS Number: 7559-04-8
Purity: 95%
Molecular Weight: 446.7
Molecular Formula: C29H50O3
* Refer to Certificate of Analysis for lot specific data (including water content).
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Tocopherylquinone, d-α is an alpha-tocopherol oxidation product. During hypoxia in rats, levels of tocopherylquinon have been found to rise. It is reported to downregulate respiratory acitvity of mitochondria. It has also displayed antioxidant activities after it is reduced to tocopherylhydroquinone.


References

1. Siegel, D., et al. 1997. Mol. Pharmacol. 52: 300-305. PMID: 9271353
2. Kanazawa, H., et al. 2000. Chem. Pharm. Bull. 48: 1462-1466. PMID: 11045451
3. Gille, L., et al. 2004. Biochem. Pharmacol. 68: 373-381. PMID: 15194009

Appearance :
Oil
Physical State :
Liquid
Solubility :
Soluble in ethanol
Storage :
Store at -20° C
Refractive Index :
n20D ~1.50
Optical Activity :
α25/D 2°, c = 2 in isooctane
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
RTECS :
DK5170000
PubChem CID :
24205
MDL Number :
MFCD00135657
EC Number :
231-450-8
SMILES :
CC1=C(C(=O)C(=C(C1=O)C)CCC(C)(CCCC(C)CCCC(C)CCCC(C)C)O)C

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Certificate of Analysis

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