Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
Express Blue Ice
Express Dry Ice
Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
TIM-2 Antibody (RMT2-1) is a high quality monoclonal TIM-2 antibody (also designated TIMD2 antibody) suitable for the detection of the TIM-2 protein of mouse origin. TIM-2 Antibody (RMT2-1) is available as the non-conjugated anti-TIM-2 antibody. CD4+ T helper lymphocytes can be divided into types 1 (Th1) and 2 (Th2) on the basis of their cytokine secretion patterns. Th1 cells and their associated cytokines are involved in cell-mediated immunity to intracellular pathogens and delayed-type hypersensitivity reactions. Th2 cells are involved in the control of extracellular helminthic infections and the promotion of atopic and allergic diseases. T cell Ig- and Mucin-domain-containing molecules (TIMs) are a family of molecules expressed on T cells. TIM-2 inhibits T cell activation in vitro and T cell-mediated disease in vivo. TIM-2 is expressed preferentially in differentiated Th2 cells, and is critical for the negative regulation of Th2 responses during autoimmune inflammation. Further understanding of the mechanisms by which TIM-2 regulates Th2-effector activity may provide insight into the therapeutic modulation of immune-mediated diseases.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Would it be possible to use this antibody for Western Blot analysis?
Asked by: zepp89
Thank you for your question. Based on our tests with this antibody we can only recommend it for detection of TIM-2 in flow cytometry with human samples. Please contact our technical service for further information.
Answered by: SCBT Heidelberg Support
Date published: 2019-01-06
If I want to use TIM-2 (RMT2-1): sc-53770 for Flow Cytometry, what starting dilution do you recommend I use?
Asked by: TinTin
We recommend a starting dilution of 1µg of antibody per million cells. Here is a link to our recommended protocol:
Answered by: Technical Support
Date published: 2017-03-24
Asked by: 小陈老师
感谢您的提问。请您联系我们的技术支持部门，我们将为您进行序列分析，回答您的相关问题。技术支持：电话(+86) 021-60936351、邮箱[email protected]。
Thank you for your inquiry. Please contact our Technical Service Asian Technical Service team at (+86) 021-60936351 or [email protected], and we would be happy to perform sequence analysis and review our data to answer any questions you may have about reactivity with related proteins.
To place an order using RMB or to ship to mainland China, please visit www.scbio.cn