Tilmicosin phosphate salt (CAS 137330-13-3)

Tilmicosin phosphate salt, a macrolide antibiotic, has been a subject of significant interest in scientific research due to its mechanism of action and potential applications in veterinary microbiology and antimicrobial studies. This compound exerts its antibacterial effects by binding to the 50S subunit of bacterial ribosomes, thereby inhibiting protein synthesis and ultimately leading to bacterial cell death. Researchers have utilized tilmicosin phosphate salt as a tool to investigate bacterial pathogenesis, antibiotic resistance mechanisms, and the molecular basis of macrolide resistance in veterinary pathogens. Studies have focused on elucidating the structural determinants of tilmicosin′s interactions with ribosomal subunits and exploring the mechanisms by which bacteria develop resistance to macrolide antibiotics. Furthermore, tilmicosin phosphate salt has been employed in research exploring alternative strategies for combating antimicrobial resistance in veterinary medicine, such as in combination with other antibiotics or adjuvant compounds to enhance its antibacterial activity against multidrug-resistant pathogens. Additionally, its pharmacokinetic properties and tissue distribution have been investigated to optimize dosing regimens and improve outcomes in veterinary species. Beyond antimicrobial research, tilmicosin phosphate salt has found applications in microbiological studies as a tool to probe bacterial physiology, antibiotic resistance mechanisms, and the development of novel antimicrobial agents. With the continuous evolution of antimicrobial resistance and the emergence of multidrug-resistant bacterial strains in veterinary settings, tilmicosin phosphate salt remains a valuable asset in scientific investigations aimed at understanding bacterial pathogenesis and developing effective strategies to combat antimicrobial resistance.