TICAM-2 Antibody (G-6) is a mouse monoclonal IgG1 (kappa light chain) provided at 200 µg/ml
raised against amino acids 142-226 mapping near the C-terminus of TICAM-2 of human origin
recommended for detection of TICAM-2 of human origin by WB, IP, IF and ELISA
m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for TICAM-2 Antibody (G-6) for WB applications. These reagents are now offered in bundles with TICAM-2 Antibody (G-6) (see ordering information below).
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possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
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SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
TICAM-1, also known as Toll-interleukin 1 receptor domain (TIR)-containing adaptor molecule, maps at chromosome 19p13.3. It can physically bind the TIR domain of Toll-like receptor 3 (TLR3) and activate the IFN-beta promoter. TLR proteins are signaling molecules that can recognize pathogen associated molecular patterns and may function as a link between the innate and adaptive immune responses. TICAM-1 mediates dsRNA-TLR3-dependent production of IFN-beta. This TICAM-1-dependent pathway is important for other TLR-IFN-beta pathways, which form part of the MyD88-independent cellular immune response. TICAM-2, a cytoplasmic protein, physically bridges TLR4 and TICAM-1 and functionally transmits LPS-TLR4 signaling to TICAM-1, which in turn activates IRF-3. In its structural features, TICAM-2 resembles Mal/TIRAP, an adapter that links TLR2/4 and MyD88.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
What is the recommended starting dilution for Western blot for TICAM-2 (G-6): sc-376356 monoclonal antibody?
Asked by: Professor Griffin
Thank you for your question. The recommended starting dilution for Western blot is 1:100 with a dilution range of 1:100-1:1000. This information, along with other technical specifications, can be found in the “datasheet” link at the top of the product page, for which I have provided the link:
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