Thioridazine·HCl is a calcium channel protein inhibitor as well as a D2DR/D4DR inhibitor. It is an intercalating agent for analyzing the integrity of double stranded DNA by using the square-wave voltammetry.
1. Swanson, D.W. 1961. Am J Psychiatry. 117: 834-835. PMID: 13774226 2. Vonvoigtlander, P.F., et al. 1975. J. Pharmacol. Exp. Ther. 193: 88-94. PMID: 166158 3. Hine, B., et al. 1979. Experientia. 35: 1631-1632. PMID: 520480 4. Snyder, S.H., et al. 1985. N. Engl. J. Med. 313: 995-1002. PMID: 2413355 5. Roth, B.L., et al. 1995. Psychopharmacology. 120: 365-368. PMID: 8524985
Soluble in water (75 mM), DMSO (100 mM), chloroform, ethanol, and methanol.
Store at room temperature
Cloned rat dopamine D4 receptor: Ki= <20 nM
pKb: 9.84 (Predicted)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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Kristiansen JE; et alKristiansen JE; et al. (PubMed ID: 26415662) Determined that small doses of Thioridazine Hydrochloride caused cytotoxicity in tubercle bacilli in lung macorphages. -SCBT Publication Review
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