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Tetracycline-d6 (CAS 2373374-42-4)

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Alternate Names:
Abramycin-d6; Liquamycin-d6; Tsiklomitsin-d6
Application:
Tetracycline-d6 is a deuterium labeled broad-spectrum antibiotic
CAS Number:
2373374-42-4
Purity:
80% Isotopic Purity ≥94%
Molecular Weight:
450.47
Molecular Formula:
C22H18D6N2O8
Supplemental Information:
This is as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Tetracycline-d6 is a deuterium-labeled analog of tetracycline, a compound that has been widely studied for its biological activity. In research applications, tetracycline-d6 is used as an isotopic label to facilitate the tracking and analysis of tetracycline through various experimental protocols. The incorporation of deuterium atoms into the tetracycline molecule allows for its differentiation from non-labeled molecules through techniques like mass spectrometry, where the additional mass of the deuterium atoms can be detected. This labeled compound is particularly useful in environmental studies, where it can help in assessing the degradation, persistence, and movement of tetracycline in ecosystems. Additionally, tetracycline-d6 serves as useful in metabolomic research to understand the metabolic pathways of tetracycline in organisms. Its use as an internal standard ensures accurate quantification and analysis in complex biological samples, aiding in the advancement of analytical chemistry methodologies.


Tetracycline-d6 (CAS 2373374-42-4) References

  1. Solid phase extraction coupled to liquid chromatography-tandem mass spectrometry analysis of sulfonamides, tetracyclines, analgesics and hormones in surface water and wastewater in Luxembourg.  |  Pailler, JY., et al. 2009. Sci Total Environ. 407: 4736-43. PMID: 19477484
  2. Solubility of antibiotics in twenty-four solvents: use in analysis.  |  WEISS, PJ., et al. 1957. Antibiot Chemother (Northfield). 7: 374-7. PMID: 24544483
  3. Antibiotics in Drinking Water in Shanghai and Their Contribution to Antibiotic Exposure of School Children.  |  Wang, H., et al. 2016. Environ Sci Technol. 50: 2692-9. PMID: 26849047
  4. Minimal selective concentrations of tetracycline in complex aquatic bacterial biofilms.  |  Lundström, SV., et al. 2016. Sci Total Environ. 553: 587-595. PMID: 26938321
  5. The distribution of veterinary antibiotics in the river system in a livestock-producing region and interactions between different phases.  |  Li, Y., et al. 2016. Environ Sci Pollut Res Int. 23: 16542-51. PMID: 27172983
  6. Levels, distributions and sources of veterinary antibiotics in the sediments of the Bohai Sea in China and surrounding estuaries.  |  Liu, X., et al. 2016. Mar Pollut Bull. 109: 597-602. PMID: 27245555
  7. Quantitative models for predicting adsorption of oxytetracycline, ciprofloxacin and sulfamerazine to swine manures with contrasting properties.  |  Cheng, D., et al. 2018. Sci Total Environ. 634: 1148-1156. PMID: 29660871
  8. Assessment of veterinary drugs present in pork kidney from a Midwest US retail market.  |  Shelver, WL. and McGarvey, AM. 2019. Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 36: 571-581. PMID: 30882287
  9. Pharmaceuticals, herbicides, and disinfectants in agricultural water sources.  |  Panthi, S., et al. 2019. Environ Res. 174: 1-8. PMID: 31015109
  10. Antibiotic contamination in a typical water-rich city in southeast China: a concern for drinking water resource safety.  |  Guo, X., et al. 2020. J Environ Sci Health B. 55: 193-209. PMID: 31658861
  11. In-feed antibiotic use changed the behaviors of oxytetracycline, sulfamerazine, and ciprofloxacin and related antibiotic resistance genes during swine manure composting.  |  Cheng, D., et al. 2021. J Hazard Mater. 402: 123710. PMID: 33254754
  12. Pressurized Liquid Extraction (PLE) and QuEChERS evaluation for the analysis of antibiotics in agricultural soils.  |  da Silva, JJ., et al. 2020. MethodsX. 7: 101171. PMID: 33318963
  13. Effects of two ecological earthworm species on tetracycline degradation performance, pathway and bacterial community structure in laterite soil.  |  Lin, Z., et al. 2021. J Hazard Mater. 412: 125212. PMID: 33524732
  14. Evaluation of Antibiotic Dissemination into the Environment and Untreated Animals, by Analysis of Oxytetracycline in Poultry Droppings and Litter.  |  Pokrant, E., et al. 2021. Animals (Basel). 11: PMID: 33802994
  15. A compilation of LD50 values in newborn and adult animals.  |  Goldenthal, EI. 1971. Toxicol Appl Pharmacol. 18: 185-207. PMID: 5542824

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Tetracycline-d6, 500 µg

sc-220216
500 µg
$1065.00

Tetracycline-d6, 1 mg

sc-220216A
1 mg
$1885.00