Terbutaline CAS: 23031-32-5
MF: C12H19NO3•1/2(H2SO4)
MW: 274.32
An agonist at β2-adrenergic receptors.

Terbutaline (CAS 23031-32-5)

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Alternate Names: Bricanyl
Application: Terbutaline Hemisulfate is an agonist at β2-adrenergic receptors
CAS Number: 23031-32-5
Purity: >99%
Molecular Weight: 274.32
Molecular Formula: C12H19NO31/2(H2SO4)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data (including water content).
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Terbutaline Hemisulfate activates β2-AR. In alveolar epithelial cells, it stimulates activity and increases expression of epithelial Na+ channels (ENaCs). Terbutaline has been shown to inhibit the production of TNF-α. Terbutaline Hemisulfate also inhibits expression of corticotropin-releasing hormone in trophoblasts.


References

1. Lui, P.W. et al. 1996. Can J Anaesth. 43(12): 1216-1219. PMID: 8955969

2. Johnson, M. 2001. Paediatr Respir Rev. 2(1): 57-62. PMID: 16263481

3. Planès, C. et al. 2002. J. Biol. Chem. 277(49): 47318-47324. PMID: 12372821

4. Aldridge, J.E. et al. 2005. Toxicol. Appl. Pharmacol. 203(2): 132-144. PMID: 15710174

5. Kontopoulos, E.V. et al. 2006. J. Matern. Fetal. Neonatal. Med. 19(11): 735-739. PMID: 17127497

6. Freund-Michel, V.C. et al. 2010. Eur. Respir. J. 35(3): 647-654. PMID: 19679606

7. Bohren, Y. et al. 2013. Neurobiol. Dis. 60 : 39-50. PMID: 23978467

8. Koseki, N. et al. 2014. J Toxicol Sci. 39(4): 579-600. PMID: 25056783

Physical State :
Solid
Solubility :
Soluble in ethanol, and methanol.
Storage :
Store at room temperature
Melting Point :
119-122° C
Boiling Point :
~419.2° C at 760 mmHg (Predicted)
Density :
~1.2 g/cm3 (Predicted)
Refractive Index :
n20D 1.57 (Predicted)
pK Values :
pKa: 9.11 (Predicted), pKb: 9.65 (Predicted)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
Merck Index :
14: 9159
MDL Number :
MFCD00278482
EC Number :
245-385-8
SMILES :
CC(C)(C)NCC(C1=CC(=CC(=C1)O)O)O.CC(C)(C)NCC(C1=CC(=CC(=C1)O)O)O.OS(=O)(=O)O

Download SDS (MSDS)

Certificate of Analysis

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Terbutaline (CAS 23031-32-5)  Product Citations

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PMID: # 28587779  Taraji, M. et al. 2017. J Chromatogr A. 1507: 53-62.

Citations 1 to 1 of 1 total
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