TEL2 Antibody (F-8) is a mouse monoclonal IgG2a κ, cited in 1 publications, provided at 200 µg/ml
raised against amino acids 111-198 mapping within an internal region of TEL2 of human origin
recommended for detection of TEL2 of human origin by WB, IP, IF and ELISA
TransCruz reagent for ChIP application (sc-376137 X, 200 µg/0.1 ml)
m-IgG Fc BP-HRP and m-IgG2a BP-HRP are the preferred secondary detection reagents for TEL2 Antibody (F-8) for WB applications. These reagents are now offered in bundles with TEL2 Antibody (F-8) (see ordering information below).
Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
Express Blue Ice
Express Dry Ice
Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
Ets-1 is the prototype member of a family of genes identified on the basis of homology to the v-Ets oncogene isolated from the E26 erythroblastosis virus. Members of the Ets gene family exhibit varied patterns of tissue expression and share a highly conserved carboxy terminal domain which contains a sequence related to the SV40 large T antigen nuclear localization sequence. This conserved carboxy domain is essential for Ets-1 binding to DNA and is likely to be responsible for the DNA binding activity of all members of the Ets gene family. TEL2, also known as ETV7 (ets variant gene 7), TREF or TELB, is a 341 amino acid nuclear protein that contains one PNT domain and one Ets DNA-binding domain. Expressed in hematopoietic tissue, TEL2 belongs to the Ets family and functions as a transcriptional repressor that binds to the DNA sequence 5′-CCGGAAGT-3′. Defects in the gene encoding TEL2 are associated with B-cell malignancies, suggesting an important role for TEL2 in carcinogenesis. Seven isoforms (designated A-G) of TEL2 exist due to alternative splicing events.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.