Anti-TEL2 Antibody (E-1) is a mouse monoclonal IgG1 κ TEL2 antibody, cited in 1 publications, provided at 200 µg/ml
raised against amino acids 111-198 mapping within an internal region of TEL2 of human origin
TEL2 Antibody (E-1) is recommended for detection of TEL2 of human origin by WB, IP, IF and ELISA
Anti-TEL2 Antibody (E-1) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
Contact our Technical Service Department (or your local Distributor) for more information on how to receive a FREE 10 µg sample of TEL2 (E-1): sc-374478.
m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for TEL2 Antibody (E-1) for WB applications. These reagents are now offered in bundles with TEL2 Antibody (E-1) (see ordering information below).
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Labware ships FedEx Ground free of charge to the contiguous US
TEL2 Antibody (E-1) is a high quality monoclonal TEL2 antibody (also designated TEL2 antibody) suitable for the detection of the TEL2 protein of human origin. TEL2 Antibody (E-1) is available as both the non-conjugated anti-TEL2 antibody form, as well as multiple conjugated forms of anti-TEL2 antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. Ets-1 is the prototype member of a family of genes identified on the basis of homology to the v-Ets oncogene isolated from the E26 erythroblastosis virus. Members of the Ets gene family exhibit varied patterns of tissue expression and share a highly conserved carboxy terminal domain which contains a sequence related to the SV40 large T antigen nuclear localization sequence. This conserved carboxy domain is essential for Ets-1 binding to DNA and is likely to be responsible for the DNA binding activity of all members of the Ets gene family. TEL2, also known as ETV7 (ets variant gene 7), TREF or TELB, is a 341 amino acid nuclear protein that contains one PNT domain and one Ets DNA-binding domain. Expressed in hematopoietic tissue, TEL2 belongs to the Ets family and functions as a transcriptional repressor that binds to the DNA sequence 5′-CCGGAAGT-3′. Defects in the gene encoding TEL2 are associated with B-cell malignancies, suggesting an important role for TEL2 in carcinogenesis. Seven isoforms (designated A-G) of TEL2 exist due to alternative splicing events.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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