TCN 238A positive allosteric mGluR-4 modulator

TCN 238 (CAS 125404-04-8)

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Synonym: (E)-4-(2-Phenylethenyl)-2-pyrimidinamine
Application: A positive allosteric mGluR-4 modulator
CAS Number: 125404-04-8
Molecular Weight: 197.24
Molecular Formula: C12H11N3
* Refer to Certificate of Analysis for lot specific data (including water content).
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TCN 238 is a positive allosteric modulator of mGluR-4 (metabotropic glutamate receptor) (EC50 = 1.0 μM for human and rat mGluR-4 receptors).

Physical State :
Solid
Solubility :
Soluble in DMSO (100 mM), and ethanol (10 mM).
Storage :
Store at 4° C
IC50 :
mGluR-4: EC5050 = 1.0 µM (human); mGlu4 receptor: EC5050 = 1.0 µM (rat)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
46911068
SMILES :
C1=CC=C(C=C1)/C=C/C2=NC(=NC=C2)N

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Certificate of Analysis

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