Anti-TBL1XR1 Antibody (L-08) is a mouse monoclonal IgG1 κ TBL1XR1 antibody, cited in 11 publications, provided at 50 µg/0.5 ml
raised against partial recombinant protein mapping to an internal region of TBL1XR1 of human origin
recommended for detection of TBL1XR1 of human origin by WB, IP, IF, IHC(P) and ELISA
Contact our Technical Service Department (or your local Distributor) for more information on how to receive a FREE 10 µg sample of TBL1XR1 (L-08): sc-100908.
m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for TBL1XR1 Antibody (L-08) for WB and IHC(P) applications. These reagents are now offered in bundles with TBL1XR1 Antibody (L-08) (see ordering information below).
Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
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SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
TBL1XR1 Antibody (L-08) is a high quality monoclonal TBL1XR1 antibody (also designated TBL1XR1 antibody) suitable for the detection of the TBL1XR1 protein of human origin. TBL1XR1 Antibody (L-08) is available as the non-conjugated anti-TBL1XR1 antibody. TBL1XR1 (transducin (beta)-like 1 X-linked receptor 1), also known as C21, DC42, IRA1 or TBLR1 (TBL1-related protein 1), is a ubiquitously expressed protein that belongs to the WD repeat EBI family of proteins. Localizing to the cytoplasm and the nucleus, TBL1XR1 contains eight WD repeats, one LisH domain and one F-box-like domain. TBL1XR1 functions as a transcriptional regulator, acting as a component of the co-repressor machinery (NCoR/SMRT complex) that is required for the activation of many transcription factors. Specifically, TBL1XR1 is essential for the recruitment of proteasome machinery and, therefore, the subsequent degradation of co-repressors upon ligand binding. The knockdown of TBL1XR1 inhibits β-catenin-mediated transcription and greatly suppresses the growth of head and neck squamous cell carcinoma cells. This suggests that TBL1XR1 may be a useful target in anti-cancer therapy.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.