Anti-TAF II p135 Antibody (22) is a mouse monoclonal IgG1 κ TAF II p135 antibody, cited in 8 publications, provided at 200 µg/ml
raised against amino acids 454-565 of TAF II p135 of human origin
recommended for detection of TAF II p135 of mouse, rat and human origin by WB, IP and IF
Contact our Technical Service Department (or your local Distributor) for more information on how to receive a FREE 10 µg sample of TAF II p135 (22): sc-136093.
m-IgG1 BP-HRP is the preferred secondary detection reagent for TAF II p135 Antibody (22) for WB applications. This reagent is now offered in a bundle with TAF II p135 Antibody (22) (see ordering information below).
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TAF II p135 Antibody (22) is a high quality monoclonal TAF II p135 antibody (also designated TAF II p135 antibody) suitable for the detection of the TAF II p135 protein of mouse, rat and human origin. TAF II p135 Antibody (22) is available as the non-conjugated anti-TAF II p135 antibody. TFIID is a general transcription factor that initiates preinitiation complex assembly through direct interaction with the TATA promoter element. Functioning as a multisubunit complex consisting of a small TATA-binding polypeptide and other TBP-associated factors (TAFs), TFIID mediates promoter responses to various transcriptional activators and repressors. TAF II p135, also known as TAF4, TAF2C, TAF2C1, TAF4A or TAFII130, is a 1,085 amino acid subunit of TFIID that accelerates transcriptional activation triggered by thyroid hormone (TR) or retinoic acid (RA). Localized to the nucleus, TAF II p135 contains one TAFH domain and is thought to bind to proteins that contain glutamine-rich domains, such as the transcription factor CREB. Via its binding to glutamine-rich proteins, TAF II p135 may be associated with neurodegenerative polyglutamine diseases, such as DRPLA (Dentatorubropallidoluysian atrophy), HD (Huntington′s disease) and SCA (Spinocerebellar ataxia).
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Can this antibody be used to detect bovine TAF II p135?
Asked by: AbPolly
Thank you for your question. Please contact our Technical Service Department and we would be happy to perform sequence analysis and review our data to answer any questions you may have about additional species reactivity.
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