SX 011 CAS: 309913-42-6
MF: C26H27ClFN3O3
MW: 483.96
A selective p38α, p38β and JNK-2 inhibitor.

SX 011 (CAS 309913-42-6)

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Application: A selective p38α, p38β and JNK-2 inhibitor
CAS Number: 309913-42-6
Molecular Weight: 483.96
Molecular Formula: C26H27ClFN3O3
* Refer to Certificate of Analysis for lot specific data (including water content).

SX 011 is a selective p38α, p38β and JNK-2 inhibitor. Reported to display no significant activity at p38γ, p38δ, ERK-2 and JNK-1.


References

1. Lee, M.R., et al. 2005. Curr. Med. Chem. 12: 2979-2994. PMID: 16378500

Physical State :
Solid
Solubility :
Soluble in DMSO (100 mM), and ethanol (100 mM).
Storage :
Store at room temperature
IC50 :
p38α: IC50 = 9 nM; p38β: IC50 = 90 nM; JNK2: IC50 = 100 nM
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
9935015
SMILES :
CN1C=C(C2=CC(=C(C=C21)Cl)C(=O)N3CCC(CC3)CC4=CC=C(C=C4)F)C(=O)C(=O)N(C)C

Download SDS (MSDS)

Certificate of Analysis

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