Molecular structure of Succinylcholine Chloride, CAS Number: 71-27-2
Succinylcholine Chloride (CAS 71-27-2)
Alternate Names:
Listenon
Application:
Succinylcholine Chloride is a neuromuscular blocking agent
CAS Number:
71-27-2
Purity:
≥99%
Molecular Weight:
361.30
Molecular Formula:
C14H30Cl2N2O4
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Succinylcholine Chloride, a quaternary ammonium compound, acts as a depolarizing agent. By binding to nicotinic receptors at the neuromuscular junction and opening ligand-gated channels like acetylcholine, it induces depolarization, inhibits neuromuscular transmission, and results in disorganized muscle contraction, followed by skeletal muscle relaxation and flaccid paralysis. The resistance of succinylcholine to acetylcholinesterases prolongs the depolarization process.
Succinylcholine Chloride (CAS 71-27-2) References
- Studies on the pharmacodynamics of succinylcholine chloride in the horse. | BELLING, TH. and BOOTH, NH. 1955. J Am Vet Med Assoc. 126: 37-42. PMID: 13221508
- Succinylcholine chloride in electroencephalography. | ANDERSON, K. and FUNK, IC. 1957. Neurology. 7: 142-5. PMID: 13400221
- The relationship between cholinesterase activity and the effects of succinylcholine chloride in the horse and cow. | STOWE, CM., et al. 1958. Cornell Vet. 48: 241-59. PMID: 13561688
- Effects of sex hormones on acute toxicity of succinylcholine chloride in mice. | LIGHT, AE. and FANELLI, RV. 1955. Arch Biochem Biophys. 56: 267-8. PMID: 14377575
- Stability of succinylcholine solutions stored at room temperature studied by nuclear magnetic resonance spectroscopy. | Adnet, F., et al. 2007. Emerg Med J. 24: 168-9. PMID: 17351219
- The rapid SERS detection of succinylcholine chloride in human plasma is based on the high affinity between quaternary ammonium salt structures. | Lin, D., et al. 2021. Spectrochim Acta A Mol Biomol Spectrosc. 263: 120172. PMID: 34273893
- Effect of thiamylal and diazepam on release of myoglobin and creatine phosphokinase by succinylcholine chloride during halothane anesthesia. | Umino, M., et al. 1985. Bull Tokyo Med Dent Univ. 32: 91-6. PMID: 3865740
- The effects of hyaluronidase on the immobilization of goats by intramuscular succinylcholine chloride. | Ward, FP., et al. 1969. Can J Comp Med. 33: 20-4. PMID: 4237290
- Physiologic effects of succinylcholine chloride in mechanically ventilated horses anesthetized with halothane in oxygen. | Benson, GJ., et al. 1979. Am J Vet Res. 40: 1411-6. PMID: 43103
- Effects of succinylcholine chloride on the response of fast and slow muscle in the cat. | Choi, WW., et al. 1984. Acta Anaesthesiol Scand. 28: 516-20. PMID: 6093420
- Diazepam and succinylcholine chloride for restraint of the American alligator. | Spiegel, RA., et al. 1984. J Am Vet Med Assoc. 185: 1335-6. PMID: 6511577
- Succinylcholine chloride as a euthanatizing agent in dogs. | Hicks, T. and Bailey, EM. 1978. Am J Vet Res. 39: 1195-7. PMID: 677539
- Chronotropic effects of succinylcholine and succinylmonocholine on the sinoatrial node. | Yasuda, I., et al. 1982. Anesthesiology. 57: 289-92. PMID: 7125266
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Rapsyn.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Succinylcholine Chloride, 10 mg | sc-215918 | 10 mg | $250.00 |