Molecular structure of Stevioside, CAS Number: 57817-89-7
Stevioside (CAS 57817-89-7)
See product citations (2)
Alternate Names:
(4α-13-[(2-O-β-D-Glucopyranosyl-β-D-glucopyranosyl)oxy]kaur-16-en-18-oic acid β-D-glucopyranosyl ester
Application:
Stevioside is a reagent that exhibits transepithelial p-aminohippurate transport
CAS Number:
57817-89-7
Purity:
≥95%
Molecular Weight:
804.87
Molecular Formula:
C38H60O18
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Stevioside is a noncaloric natural sweetener, 300 times more potent than sucrose. It inhibits transepithelial transport of p-aminohippurate (PAH) by interfering with the organic anion transport system. At 0.5-1 mM, it showed no interaction with any organic anion transporters (OAT).Stevioside reportedly has genotoxic effects in cultured mammalian cells. Stevioside-induced ROS-mediated apoptosis was studied in human breast cancer cells.
Stevioside (CAS 57817-89-7) References
- Stevioside methanol tetra-solvate. | Wu, Y., et al. 2013. Acta Crystallogr Sect E Struct Rep Online. 69: o410-1. PMID: 23476589
- Stevioside, a diterpenoid glycoside, shows anti-inflammatory property against Dextran Sulphate Sodium-induced ulcerative colitis in mice. | Alavala, S., et al. 2019. Eur J Pharmacol. 855: 192-201. PMID: 31075241
- Stevioside Has the Maximum Biological Activity among Natural Stevia Diterpenes. | Ogorodnova, UA., et al. 2020. Dokl Biol Sci. 492: 79-82. PMID: 32632831
- Stevioside protects against rhabdomyolysis-induced acute kidney injury through PPAR-γ agonism in rats. | Kaur, T., et al. 2021. Drug Dev Res. 82: 59-67. PMID: 32737941
- Stevioside inhibits unilateral ureteral obstruction-induced kidney fibrosis and upregulates renal PPARγ expression in mice. | Shen, W., et al. 2020. J Food Biochem. 44: e13520. PMID: 33047331
- Stevioside Activates AMPK to Suppress Inflammation in Macrophages and Protects Mice from LPS-Induced Lethal Shock. | Wei, F., et al. 2021. Molecules. 26: PMID: 33562046
- Study on the bioavailability of stevioside-encapsulized lutein and its mechanism. | Dai, Z., et al. 2021. Food Chem. 354: 129528. PMID: 33756320
- Molecular docking analysis of stevioside with Akt and PPARγ. | Deenadayalan, A., et al. 2021. Bioinformation. 17: 283-288. PMID: 34393447
- Stevioside ameliorates hyperglycemia and glucose intolerance, in a diet-induced obese zebrafish model, through epigenetic, oxidative stress and inflammatory regulation. | Dandin, E., et al. 2022. Obes Res Clin Pract. 16: 23-29. PMID: 35031270
- Stevioside inhibits lipopolysaccharide-induced epithelial-to-mesenchymal transition of NRK-52E cells by PPARγ activation. | Shen, W., et al. 2022. Immunopharmacol Immunotoxicol. 44: 287-294. PMID: 35139741
- Stevioside Enhances the Anti-Adipogenic Effect and β-Oxidation by Activating AMPK in 3T3-L1 Cells and Epididymal Adipose Tissues of db/db Mice. | Park, M., et al. 2022. Cells. 11: PMID: 35406641
- High-throughput screening identifies stevioside as a potent agent to induce apoptosis in bladder cancer cells. | Chen, C., et al. 2022. Biochem Pharmacol. 203: 115166. PMID: 35820501
- Stevioside attenuates osteoarthritis via regulating Nrf2/HO-1/NF-κB pathway. | Wu, J., et al. 2023. J Orthop Translat. 38: 190-202. PMID: 36439628
- Stevia and Stevioside Attenuate Liver Steatosis through PPARα-Mediated Lipophagy in db/db Mice Hepatocytes. | Park, M., et al. 2022. Antioxidants (Basel). 11: PMID: 36552704
Inhibitor of:
Trcg1.Activator of:
T1R3.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Stevioside, 10 mg | sc-272502 | 10 mg | $114.00 |