Stevensine is a dibrominated alkaloid. Deters feeding of predatory fishes. Exhibits antitumor and weak antimicrobial activity.
Synthesis of C(11)N(5) Marine Sponge Alkaloids: (+/-)-Hymenin, Stevensine, Hymenialdisine, and Debromohymenialdisine: Y.Z. Xu, et al.; J. Org. Chem. 62, 456 (1997) Chemical defense of the caribbean reef sponge Axinella corrugata against predatory fishes: D.M. Wilson, et al.; J. Chem. Ecology 25, 2811 (1999) Antimicrobial activity of Caribbean sponge extracts: R.W. Newbold, et al.; Aqu. Microb. Ecol. 19, 279 (1999) In vitro culture of the tropical sponge Axinella corrugata (Demospongiae): effect of food cell concentration on growth, clearance rate, and biosynthesis of stevensine: A.R. Duckworth, et al.; Mar. Biotechnol. (NY) 5, 519 (2003) Cyclic heptapeptides from the Jamaican sponge Stylissa caribica: R. Mohammed, et al.; J. Nat. Prod. 69, 1739 (2006) Disturbance of voltage-induced cellular calcium entry by marine dimeric and tetrameric pyrrole--imidazole alkaloids: U. Bickmeyer, et al.; Toxicon 50, 490 (2007)
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