Stearic Acid, an anti-inflammatory agent, is the hydrogenation product of linoleic acid. This compound has been shown to induce a decrease of cell growth and adhesion and increase hydrophobic properties of collagen films. This was achieved via reaction of lysyl amino groups of the α-chain of collagen films with stearate, which causes a decrease in chemical groups exposed on the surface of the films. Stearic Acid has been noted to induce an increase in ICAM-1 expression in cells, via an increase in phosphorylation of the transcriptional regulator NFκB.
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Soluble in ethanol (~20 mg/ml), DMSO (~10 mg/ml), DMF (~30 mg/ml), CCl4 (1 g/6m), chloroform, acetone, and carbondisulfide. Insoluble in water.
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