Squalane (CAS 111-01-3)
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Squalane is a highly refined lipid derived from the hydrogenation of squalene, a naturally occurring polyunsaturated hydrocarbon. Its molecular structure grants it unique properties, such as exceptional stability and resistance to oxidation, making it a useful compound in various research applications. In scientific studies, squalane is utilized as a high-performance chromatographic solvent and carrier in systems where inertness and minimal reactivity are necessary. Its inert nature also makes it ideal for use in controlled delivery systems in material science, where its ability to form stable emulsions facilitates the precise deployment of active compounds. The physicochemical characteristics of squalane, such as its non-polarity and ability to spread evenly over surfaces, are leveraged in the development of biomimetic membranes and model skin systems, aiding in the exploration of permeation and barrier properties in synthetic and biological materials.
Squalane (CAS 111-01-3) References
- Squalene and squalane emulsions as adjuvants. | Allison, AC. 1999. Methods. 19: 87-93. PMID: 10525443
- Squalane is in the midplane of the lipid bilayer: implications for its function as a proton permeability barrier. | Hauss, T., et al. 2002. Biochim Biophys Acta. 1556: 149-54. PMID: 12460672
- Biological importance and applications of squalene and squalane. | Kim, SK. and Karadeniz, F. 2012. Adv Food Nutr Res. 65: 223-33. PMID: 22361190
- Effect of squalane on mebendazole-loaded Compritol® nanoparticles. | Graves, RA., et al. 2015. J Biomater Sci Polym Ed. 26: 868-80. PMID: 26062393
- Probing the Evaporation Dynamics of Mixed SOA/Squalane Particles Using Size-Resolved Composition and Single-Particle Measurements. | Robinson, ES., et al. 2015. Environ Sci Technol. 49: 9724-32. PMID: 26158746
- Purported fragile-to-Arrhenius crossover in squalane. | Bair, S. 2017. Proc Natl Acad Sci U S A. 114: E8805-E8806. PMID: 29073024
- Experimental and simulation study of the high-pressure behavior of squalane and poly-α-olefins. | Prentice, IJ., et al. 2020. J Chem Phys. 152: 074504. PMID: 32087637
- Oligomer/Polymer Blend Phase Diagram and Surface Concentration Profiles for Squalane/Polybutadiene: Experimental Measurements and Predictions from SAFT-γ Mie and Molecular Dynamics Simulations. | Tasche, J., et al. 2020. Macromolecules. 53: 2299-2309. PMID: 32308214
- Effectiveness and tolerability of a squalane and dimethicone-based treatment for head lice. | Martínez de Murguía Fernández, L., et al. 2021. Parasitol Res. 120: 1883-1890. PMID: 33797611
- A gas chromatography-mass spectrometry method for quantifying squalane and squalene in aerosol emissions of electronic cigarette, or vaping, products. | Cowan, EA., et al. 2022. Talanta. 238: 122985. PMID: 34857320
- Inverse ISAsomes in Bio-Compatible Oils-Exploring Formulations in Squalane, Triolein and Olive Oil. | Trummer, F., et al. 2022. Nanomaterials (Basel). 12: PMID: 35407249
- The Quantitation of Squalene and Squalane in Bronchoalveolar Lavage Fluid Using Gas Chromatography Mass Spectrometry. | Cowan, EA., et al. 2022. Front Chem. 10: 874373. PMID: 35464226
- Effect of squalane-based emulsion on polyphenols skin penetration: Ex vivo skin study. | Oliveira, ALS., et al. 2022. Colloids Surf B Biointerfaces. 218: 112779. PMID: 35994992
- Development and Efficacy Evaluation of a Novel Nano-Emulsion Adjuvant for a Foot-and-Mouth Disease Virus-like Particles Vaccine Based on Squalane. | Shi, X., et al. 2022. Nanomaterials (Basel). 12: PMID: 36432220
- Effect of squalane on hexachlorobenzene (HCB) concentrations in tissues of mice. | Richter, E. and Schäfer, SG. 1982. J Environ Sci Health B. 17: 195-203. PMID: 7096897
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Squalane, 5 g | sc-251065 | 5 g | $38.00 | |||
Squalane, 100 g | sc-251065A | 100 g | $47.00 |