Sphingolactone-24A selective and irreversible inhibitor of neutral sphingomyelinase

Sphingolactone-24 (CAS 881177-99-7)

Sphingolactone-24 | CAS 881177-99-7 is rated 5.0 out of 5 by 1.
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Application: A selective and irreversible inhibitor of neutral sphingomyelinase
CAS Number: 881177-99-7
Purity: >95%
Molecular Weight: 323.4
Molecular Formula: C18H29NO4
* Refer to Certificate of Analysis for lot specific data (including water content).
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Sphingolactone-24 is a selective and irreversible inhibitor of N-SMase (neutral sphingomyelinase).


References

Sphingolactones: selective and irreversible inhibitors of neutral sphingomyelinase: V. Wascholowski & A. Giannis; Angew. Chem. Int. Ed. Engl. 45, 827 (2006)

Physical State :
Solid
Solubility :
Soluble in DMSO (10mg/ml).
Storage :
Store at -20° C
Melting Point :
217.28° C (Predicted)
Boiling Point :
564.64° C at 760 mmHg (Predicted)
Density :
1.06 g/cm3
Refractive Index :
n20D 1.50 (Predicted)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
11681358
MDL Number :
MFCD14635424
SMILES :
CCCCCCC1C[C@@H](OC1=O)[C@H](CO)NC(=O)/C=C/C=C/C

Download SDS (MSDS)

Certificate of Analysis

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Rated 5 out of 5 by from Luther et al Luther et al. (PubMed ID 23114219) used the sphingomyelinase inhibitor, sphingolactone-24, to block the effect of brain-derived neurotrophic factor (BDNF). -SCBT Publication Review
Date published: 2015-02-26
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