Sphingolactone-24 is a selective and irreversible inhibitor of N-SMase (neutral sphingomyelinase).
Sphingolactones: selective and irreversible inhibitors of neutral sphingomyelinase: V. Wascholowski & A. Giannis; Angew. Chem. Int. Ed. Engl. 45, 827 (2006)
Soluble in DMSO (10mg/ml).
Store at -20° C
217.28° C (Predicted)
564.64° C at 760 mmHg (Predicted)
n20D 1.50 (Predicted)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Download SDS (MSDS)
Certificate of Analysis
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Rated 5 out of
Luther et alLuther et al. (PubMed ID 23114219) used the sphingomyelinase inhibitor, sphingolactone-24, to block the effect of brain-derived neurotrophic factor (BDNF). -SCBT Publication Review
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