Sodium Pyruvate Solution 100 mM (100X), liquid, sodium pyruvate is utilized as a component in culture broth and media. It is utilized by cells as an intermediate compound in the metabolism of carbohydrates, proteins, and fats. It is involved with amino acid metabolism and initiates the Kreb′s cycle. In thiamine deficiency, its oxidation is retarded and it accumulates in the tissues, especially in nervous structures. A protcol that uses sodium pyruvate to establish stably transfected human B cell lines has been published. The 100 mM solution should be diluted 1:100 for most cell culture applications.
1. Brielmeier, M., et al. 1998. Nucleic Acids Res. 26: 2082-2085. PMID: 9547263 2. Geshi, M., et al. 2000. Biol. Reprod. 63: 1730-1734. PMID: 11090443 3. Jiang, X.,and Doyle, M.P. 2000. J. Clin. Microbiol. 38: 1984-1987. PMID: 10790135 4. Kuo, T.M., et al. 2002. Curr. Microbiol. 45: 265-271. PMID: 12192524
100mM (11 mg/mL) in purified H2O
Store at 4° C
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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Sodium Pyruvate Solution 100 mM (100X) Product Citations
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did Sodium Pyruvate Solution 100 mM (100X) (CAS 113-24-6 (solid)) are sterile solution or not?and what is the sterilization method?
Asked by: ENRA
Thank you for your question. This product has not been specifically tested for cell culture use and is not cell culture grade, however, most products can still be used in cell culture applications by following basic cell culture protocols, e.g. using cell culture grade/sterilized solvents, aseptic technique, and sterilely filtering in a sterile hood. Here is a link to the most recent Certificate of Analysis:
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Various publications have cited the use ofVarious publications have cited the use of Sodium Pyruvate Solution as a component in culture broth and media. It is utilized by cells as an intermediate compound in the metabolism of carbohydrates, proteins, and fats. It is also involved with amino acid metabolism and initiates the Kreb s cycle. -SCBT Publication Review
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