SO Antibody (G-4) is a mouse monoclonal mouse IgG2b κ (kappa light chain) provided at 200 µg/ml
raised against amino acids 246-545 mapping at the C-terminus of SO of human origin
recommended for detection of SO of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA
m-IgGκ BP-HRP (mouse IgGκ binding protein-HRP) is the preferred secondary detection reagent for SO Antibody (G-4) for WB and IHC(P) applications. This reagent is now offered in a bundle with SO Antibody (G-4) (see ordering information below). For additional m-IgGκ BP conjugates see our complete list of Mouse IgG Binding Proteins.
Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
Express Blue Ice
Express Dry Ice
Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
Sulfite oxidase (SO), a homodimeric protein that localizes to the intermembrane space of mitochondria, catalyzes the oxidation of sulfite to sulfate, the terminal reaction in the oxidative degradation of the sulfur amino acids cysteine and methionine. Genetic deficiency of SO contributes to neurological abnormalities and often leads to death at an early age. Mutation of Arginine 160 in humans decreases the intramolecular electron transfer (IET) rate, which contributes to the fatality of this genetic disorder. Also, the tyrosine 343 residue in humans plays an important role in both substrate binding and oxidation of sulfite by SO. The human SO gene maps to chromosome 12, and shows high expression in liver, kidney, skeletal muscle, heart, placenta and brain.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.