Anti-SO Antibody (F-6) is a mouse monoclonal IgG2b (kappa light chain) SO antibody provided at 200 µg/ml
specific for an epitope mapping between amino acids 110-127 near the N-terminus of SO of human origin
Anti-SO Antibody (F-6) is recommended for detection of precursor and mature SO of mouse, rat and human origin by WB, IP, IF and ELISA
Anti-SO Antibody (F-6) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
Contact our Technical Service Department (or your local Distributor) for more information on how to receive a FREE 10 µg sample of SO (F-6): sc-393688.
m-IgG Fc BP-HRP (mouse IgG Fc binding protein-HRP) and m-IgGκ BP-HRP (mouse IgGκ binding protein-HRP) are the preferred secondary detection reagents for SO Antibody (F-6) for WB applications. These reagents are now offered in bundles with SO Antibody (F-6) (see ordering information below).
Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
Express Blue Ice
Express Dry Ice
Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
SO Antibody (F-6) is a high quality monoclonal SO antibody (also designated SO antibody) suitable for the detection of the SO protein of mouse, rat and human origin. SO Antibody (F-6) is available as both the non-conjugated anti-SO antibody form, as well as multiple conjugated forms of anti-SO antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. Sulfite oxidase (SO), a homodimeric protein that localizes to the intermembrane space of mitochondria, catalyzes the oxidation of sulfite to sulfate, the terminal reaction in the oxidative degradation of the sulfur amino acids cysteine and methionine. Genetic deficiency of SO contributes to neurological abnormalities and often leads to death at an early age. Mutation of Arginine 160 in humans decreases the intramolecular electron transfer (IET) rate, which contributes to the fatality of this genetic disorder. Also, the tyrosine 343 residue in humans plays an important role in both substrate binding and oxidation of sulfite by SO. The human SO gene maps to chromosome 12, and shows high expression in liver, kidney, skeletal muscle, heart, placenta and brain.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences